St Mark's Hospital, Northwick Park, Watford Road, Harrow, Middlesex, HA1 3UJ, UK.
Expert Rev Gastroenterol Hepatol. 2011 Dec;5(6):731-43. doi: 10.1586/egh.11.80.
Esophageal cancers have traditionally been diagnosed late and prognosis has been dire. For many years the only real treatment option was esophagectomy with substantial morbidity and mortality. This situation has now changed dramatically. Improvements have been achieved in surgical outcomes and there is an array of new effective treatment options now available, particularly for the increasing proportion diagnosed with early-stage disease. Minimally invasive endoscopic therapies can now prevent, cure or palliate esophageal cancers. This article aims to investigate the role and evidence base for these new therapeutic options.
食管癌传统上被诊断较晚，预后不佳。多年来，唯一真正的治疗选择是有较高发病率和死亡率的食管切除术。这种情况现在已经发生了巨大的变化。手术结果得到了改善，并且现在有一系列新的有效治疗选择，特别是对于越来越多被诊断为早期疾病的患者。微创内镜治疗现在可以预防、治愈或缓解食管癌。本文旨在探讨这些新治疗选择的作用和证据基础。
