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口腔微生物群与牙周健康和疾病的关系。

The relationship of the oral microbiotia to periodontal health and disease.

机构信息

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and The London, Queen Mary University of London, London E1 2AT, UK.

出版信息

Cell Host Microbe. 2011 Oct 20;10(4):302-6. doi: 10.1016/j.chom.2011.09.008.

DOI:10.1016/j.chom.2011.09.008
PMID:22018230
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3216488/
Abstract

The oral microbial community represents the best-characterized consortium associated with the human host. There are strong correlations between the qualitative composition of the oral microbiota and clinically healthy or diseased states. However, additional studies are needed to elucidate the mechanisms that define these microbial/host relationships.

摘要

口腔微生物群落代表了与人类宿主最相关的最佳特征性联合体。口腔微生物群落的定性组成与临床健康或疾病状态之间存在很强的相关性。然而,需要进一步的研究来阐明定义这些微生物/宿主关系的机制。

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本文引用的文献

1
CORE: a phylogenetically-curated 16S rDNA database of the core oral microbiome.CORE:一个经过系统发育学筛选的核心口腔微生物组 16S rDNA 数据库。
PLoS One. 2011 Apr 22;6(4):e19051. doi: 10.1371/journal.pone.0019051.
2
Has the use of molecular methods for the characterization of the human oral microbiome changed our understanding of the role of bacteria in the pathogenesis of periodontal disease?分子方法在人类口腔微生物组特征描述中的应用是否改变了我们对细菌在牙周病发病机制中作用的认识?
J Clin Periodontol. 2011 Mar;38 Suppl 11:7-16. doi: 10.1111/j.1600-051X.2010.01679.x.
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The human oral microbiome.人类口腔微生物组。
J Bacteriol. 2010 Oct;192(19):5002-17. doi: 10.1128/JB.00542-10. Epub 2010 Jul 23.
4
Comprehensive analysis of gene expression in the junctional epithelium by laser microdissection and microarray analysis.应用激光微切割和微阵列分析技术对结合上皮细胞中基因表达的综合分析。
J Periodontal Res. 2010 Oct;45(5):618-25. doi: 10.1111/j.1600-0765.2010.01276.x. Epub 2010 Jun 10.
5
Periodontitis: a polymicrobial disruption of host homeostasis.牙周炎:一种宿主内稳态的微生物多样性破坏。
Nat Rev Microbiol. 2010 Jul;8(7):481-90. doi: 10.1038/nrmicro2337.
6
Oral multispecies biofilm development and the key role of cell-cell distance.口腔多物种生物膜的形成与细胞-细胞间距的关键作用
Nat Rev Microbiol. 2010 Jul;8(7):471-80. doi: 10.1038/nrmicro2381.
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Genetic and environmental risk factors for chronic periodontitis and aggressive periodontitis.慢性牙周炎和侵袭性牙周炎的遗传及环境风险因素。
Periodontol 2000. 2010 Jun;53:138-53. doi: 10.1111/j.1600-0757.2010.00340.x.
8
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PLoS One. 2010 Feb 24;5(2):e9321. doi: 10.1371/journal.pone.0009321.
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Streptococcus adherence and colonization.链球菌的黏附和定植。
Microbiol Mol Biol Rev. 2009 Sep;73(3):407-50, Table of Contents. doi: 10.1128/MMBR.00014-09.