Suppr超能文献

年轻女性乳腺癌治疗后的妊娠并不会对预后产生不利影响。

Pregnancy after treatment of breast cancer in young women does not adversely affect the prognosis.

机构信息

Breast Cancer Unit, Service of Gynecology, Hospital Vall d'Hebron, Barcelona, Spain.

出版信息

Breast. 2012 Jun;21(3):272-5. doi: 10.1016/j.breast.2011.10.001. Epub 2011 Oct 21.

Abstract

We assessed whether pregnancy after breast cancer in patients younger than 36 years of age affects the prognosis. Of 115 women with breast cancer followed for a mean of 6 years, 18 became pregnant (median time between diagnosis and the first pregnancy 44.5 months). Voluntary interruption of pregnancy was decided by 8 (44.4%) women. Significant differences in prognostic factors between pregnant and non-pregnant women were not observed. Pregnant women showed a lower frequency of positive estrogen receptors (41%) than non-pregnant (64%) (P=0.06). At 5 years of follow-up, 100% of women in the pregnant group and 80% in the non-pregnant group were alive. The percentages of disease-free women were 94% and 64%, respectively (P=0.009). Breast cancer patients presented a high number of unwanted pregnancies. Pregnancy after breast cancer not only did not adversely affect prognosis of the neoplasm but also may have a protective effect.

摘要

我们评估了 36 岁以下乳腺癌患者的妊娠是否会影响预后。在平均随访 6 年的 115 名乳腺癌患者中,有 18 名怀孕(诊断后首次怀孕的中位数时间为 44.5 个月)。8 名(44.4%)妇女决定自愿终止妊娠。未观察到妊娠和未妊娠妇女之间的预后因素存在显著差异。怀孕组的雌激素受体阳性率(41%)低于未妊娠组(64%)(P=0.06)。5 年随访时,怀孕组 100%的妇女和未妊娠组 80%的妇女存活。无病妇女的百分比分别为 94%和 64%(P=0.009)。乳腺癌患者有大量意外怀孕。乳腺癌后的妊娠不仅没有对肿瘤的预后产生不利影响,而且可能具有保护作用。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验