Aberdeen Fertility Centre, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZL, UK.
Reprod Biomed Online. 2011 Dec;23(6):717-23. doi: 10.1016/j.rbmo.2011.07.018. Epub 2011 Sep 5.
Obesity is becoming a serious problem, especially in industrialized societies. This study was designed to explore the association between body mass index (BMI) and semen quality. Semen analysis and demographic data were collected from male partners of couples undergoing fertility investigations in a referral fertility centre. Men were classified into groups according to their BMI (A, <18.5; B, 18.5-24.99; C, 25-29.99; D, ≥30 kg/m(2)). Data from 2035 men were analysed using logistic regression. There were 18, 839, 909 and 269 men in groups A, B, C and D, respectively. Taking group B as the reference, adjusted odds ratios (95% CI) for groups A, C and D for semen volume <2 ml were 1.57 (0.49-5.01), 1.06 (0.82-1.38) and 1.69 (1.20-2.38), respectively; for sperm morphology <15%, 1.44 (0.45-4.61), 1.07 (0.86-1.33) and 1.50 (1.06-2.09); for sperm concentration <20 million/ml, 0.46 (0.10-2.07), 1.03 (0.82-1.31) and 1.00 (0.72-1.41); and for motility <50%, 2.62 (0.73-9.45), 0.96 (0.78-1.18) and 0.75 (0.56-1.01). In conclusion, obese men are more likely to have lower semen volume and fewer morphologically normal spermatozoa than men with normal BMI.
肥胖正成为一个严重的问题，尤其是在工业化社会。本研究旨在探讨体重指数（BMI）与精液质量之间的关系。在一家转诊生育中心，对接受生育调查的夫妇的男性伴侣进行了精液分析和人口统计学数据收集。根据 BMI（A，<18.5；B，18.5-24.99；C，25-29.99；D，≥30 kg/m(2)）将男性分为几组。使用逻辑回归分析了 2035 名男性的数据。A、B、C 和 D 组分别有 18、839、909 和 269 名男性。以 B 组为参照，A、C 和 D 组精液量<2ml 的校正比值比（95%CI）分别为 1.57（0.49-5.01）、1.06（0.82-1.38）和 1.69（1.20-2.38）；精子形态<15%，1.44（0.45-4.61）、1.07（0.86-1.33）和 1.50（1.06-2.09）；精子浓度<2000 万/ml，0.46（0.10-2.07）、1.03（0.82-1.31）和 1.00（0.72-1.41）；以及活力<50%，2.62（0.73-9.45）、0.96（0.78-1.18）和 0.75（0.56-1.01）。总之，肥胖男性的精液量较低，形态正常的精子较少，而 BMI 正常的男性则较少。
