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依那普利导致儿童严重低钠血症和意识改变。

Enalapril induced severe hyponatremia and altered sensorium in a child.

机构信息

Department of Pediatrics, Lokmanya Tilak Municipal General Hospital and Medical College, Sion, Mumbai, India.

出版信息

Indian J Pharmacol. 2011 Sep;43(5):605-6. doi: 10.4103/0253-7613.84984.

DOI:10.4103/0253-7613.84984
PMID:22022012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3195139/
Abstract

Enalapril is an angiotensin converting enzyme inhibitor widely used in children for treatment of hypertension and congestive cardiac failure. We report a 5-year-old boy who developed severe hyponatremia and altered sensorium on enalapril therapy. The serum sodium gradually became normal within 3 days. The patient's sensorium improved significantly on correction of hyponatremia. Through this case, we highlight the importance of monitoring serum sodium in patients on enalapril therapy.

摘要

依那普利是一种血管紧张素转换酶抑制剂，广泛用于儿童治疗高血压和充血性心力衰竭。我们报告了一例 5 岁男孩在依那普利治疗期间发生严重低钠血症和意识改变。血清钠在 3 天内逐渐恢复正常。低钠血症纠正后，患者的意识状态显著改善。通过这个病例，我们强调了在依那普利治疗的患者中监测血清钠的重要性。

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引用本文的文献

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Syndrome of inappropriate secretion of antidiuretic hormone associated with angiotensin-converting enzyme inhibitor therapy in the perioperative period.围手术期与血管紧张素转换酶抑制剂治疗相关的抗利尿激素分泌不当综合征
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本文引用的文献

1
Angiotensin-converting enzyme inhibitor-induced syndrome of inappropriate secretion of antidiuretic hormone: case report and review of the literature.血管紧张素转换酶抑制剂诱发的抗利尿激素分泌不当综合征：病例报告及文献复习
Clin Pharmacol Ther. 2002 Jun;71(6):503-7. doi: 10.1067/mcp.2002.124520.
2
Angiotensin II receptor blockers. A new class of antihypertensive drugs.血管紧张素II受体阻滞剂。一类新型抗高血压药物。
Arch Fam Med. 1996 Jun;5(6):351-6. doi: 10.1001/archfami.5.6.351.
3
Hyponatremia due to enalapril in an elderly patient. A case report.老年患者因依那普利导致低钠血症。病例报告。
Arch Fam Med. 1993 Jul;2(7):791-3. doi: 10.1001/archfami.2.7.791.
4
A method for estimating the probability of adverse drug reactions.一种估算药物不良反应概率的方法。
Clin Pharmacol Ther. 1981 Aug;30(2):239-45. doi: 10.1038/clpt.1981.154.
5
Plasma angiotensin II concentrations and experimentally induced thirst.血浆血管紧张素II浓度与实验性诱发的口渴感。
Am J Physiol. 1981 Mar;240(3):R229-34. doi: 10.1152/ajpregu.1981.240.3.R229.
6
Stimulation of ADH release by the renin-angiotensin system.肾素-血管紧张素系统对抗利尿激素释放的刺激作用。
Am J Physiol. 1970 Jun;218(6):1555-9. doi: 10.1152/ajplegacy.1970.218.6.1555.
7
Angiotensin converting enzyme inhibitors.血管紧张素转换酶抑制剂
Br Med J (Clin Res Ed). 1988 Feb 27;296(6622):618-20. doi: 10.1136/bmj.296.6622.618.