依那普利导致儿童严重低钠血症和意识改变。
Enalapril induced severe hyponatremia and altered sensorium in a child.
机构信息
Department of Pediatrics, Lokmanya Tilak Municipal General Hospital and Medical College, Sion, Mumbai, India.
出版信息
Indian J Pharmacol. 2011 Sep;43(5):605-6. doi: 10.4103/0253-7613.84984.
Abstract
Enalapril is an angiotensin converting enzyme inhibitor widely used in children for treatment of hypertension and congestive cardiac failure. We report a 5-year-old boy who developed severe hyponatremia and altered sensorium on enalapril therapy. The serum sodium gradually became normal within 3 days. The patient's sensorium improved significantly on correction of hyponatremia. Through this case, we highlight the importance of monitoring serum sodium in patients on enalapril therapy.
摘要
依那普利是一种血管紧张素转换酶抑制剂，广泛用于儿童治疗高血压和充血性心力衰竭。我们报告了一例 5 岁男孩在依那普利治疗期间发生严重低钠血症和意识改变。血清钠在 3 天内逐渐恢复正常。低钠血症纠正后，患者的意识状态显著改善。通过这个病例，我们强调了在依那普利治疗的患者中监测血清钠的重要性。
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本文引用的文献
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Angiotensin-converting enzyme inhibitor-induced syndrome of inappropriate secretion of antidiuretic hormone: case report and review of the literature.血管紧张素转换酶抑制剂诱发的抗利尿激素分泌不当综合征：病例报告及文献复习
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