University of Missouri-Kansas City, School of Dentistry, Kansas City, MO 64108, USA.
J Dent. 2012 Jan;40(1):57-63. doi: 10.1016/j.jdent.2011.10.004. Epub 2011 Oct 18.
To investigate the correlation of the chemical interaction between model self-etching adhesives and dentine with the degree of conversion (DC) of the adhesives.
The model self-etching adhesives contained bis[2-methacryloyloxy)ethyl] phosphate (2MP) and 2-hydroxyethyl methacrylate (HEMA) with a mass ratio of 1/1, and 0-40% water contents, respectively. The adhesives were applied either onto the prepared dentine surface or unreactive substrates (such as glass slides), agitated for 15s, then light-cured for 40s. The DCs of the adhesives were determined using micro-Raman spectral and mapping analysis.
The DCs of the adhesives cured on the dentine substrate were found to be significantly higher than those on the unreactive glass substrate. Moreover, the DCs of the adhesives displayed a decreasing trend as the distance from the dentine surface became greater. The chemical interaction of the acidic 2MP/HEMA adhesives with the mineral apatite in dentine was proposed to play a significant role for the observations. The chemical interaction could be validated by the spectral comparison in the phosphate regions of 1100 cm(-1) and 960 cm(-1) in the Raman spectra. The results also revealed a notable influence of water content on the DC of adhesives. The DCs of the adhesive at 10% water content exhibited the highest DC level for both substrates.
Interaction with dentine dramatically improved the degree of conversion of self-etching adhesives. Our ability to chemically characterise the a/d interface including in situ detection of the DC distribution is very important in understanding self-etching adhesive bonding under in vivo conditions.
研究模型自酸蚀黏合剂与牙本质之间的化学相互作用与黏合剂转化率（DC）的相关性。
模型自酸蚀黏合剂包含双[2-（甲基丙烯酰氧基）乙基]磷酸酯（2MP）和 2-羟乙基甲基丙烯酸酯（HEMA），质量比为 1/1，分别含有 0-40%的含水量。将黏合剂应用于制备好的牙本质表面或无反应性基底（如载玻片）上，搅拌 15s，然后光固化 40s。使用微拉曼光谱和映射分析来确定黏合剂的 DC。
发现黏合剂在牙本质基底上固化的 DC 明显高于在无反应性玻璃基底上固化的 DC。此外，随着与牙本质表面的距离增大，黏合剂的 DC 呈下降趋势。酸性 2MP/HEMA 黏合剂与牙本质中矿物质磷灰石的化学相互作用被认为对这些观察结果起着重要作用。可以通过在拉曼光谱中磷酸盐区域 1100cm(-1)和 960cm(-1)处的光谱比较来验证这种化学相互作用。结果还表明，含水量对黏合剂 DC 有显著影响。在两种基底上，含水量为 10%的黏合剂的 DC 最高。
与牙本质的相互作用显著提高了自酸蚀黏合剂的 DC。我们能够对 a/d 界面进行化学表征，包括对 DC 分布的原位检测，这对于理解体内条件下自酸蚀黏合非常重要。
