Chen C, Niu L-N, Xie H, Zhang Z-Y, Zhou L-Q, Jiao K, Chen J-H, Pashley D H, Tay F R
Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University; Department of Operative Dentistry & Endodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, Jiangsu, China.
State Key Laboratory of Military Stomatology, Department of Prosthodontics, School of Stomatology, Fourth Military Medical University, Xi'an, Shaanxi, China.
J Dent. 2015 May;43(5):525-36. doi: 10.1016/j.jdent.2015.03.004. Epub 2015 Mar 20.
Multi-mode universal adhesives offer clinicians the choice of using the etch-and-rinse technique, selective enamel etch technique or self-etch technique to bond to tooth substrates. The present study examined the short-term in vitro performance of five universal adhesives bonded to human coronal dentine.
Two hundred non-carious human third molars were assigned to five groups based on the type of the universal adhesives (Prime&Bond Elect, Scotchbond Universal, All-Bond Universal, Clearfil Universal Bond and Futurabond U). Two bonding modes (etch-and-rinse and self-etch) were employed for each adhesive group. Bonded specimens were stored in deionized water for 24h or underwent a 10,000-cycle thermocycling ageing process prior to testing (N=10). Microtensile bond testing (μTBS), transmission electron microscopy (TEM) of resin-dentine interfaces in non-thermocycled specimens and scanning electron microscopy (SEM) of tracer-infused water-rich zones within hybrid layers of thermocycled specimens were performed.
Both adhesive type and testing condition (with/without thermocycling) have significant influences on μTBS. The use of each adhesive in either the etch-and-rinse or self-etch application mode did not result in significantly different μTBS to dentine. Hybrid layers created by these adhesives in the etch-and-rinse bonding mode and self-etch bonding mode were ∼5μm and ≤0.5μm thick respectively. Tracer-infused regions could be identified within the resin-dentine interface from all the specimens prepared.
The increase in versatility of universal adhesives is not accompanied by technological advances for overcoming the challenges associated with previous generations of adhesives. Therapeutic adhesives with bio-protective and bio-promoting effects are still lacking in commercialized adhesives.
Universal adhesives represent manufacturers' attempt to introduce versatility in product design via adaptation of a single-bottle self-etch adhesive for other application modes without compromising its bonding effectiveness.
多模式通用型粘结剂为临床医生提供了采用酸蚀冲洗技术、选择性釉质酸蚀技术或自酸蚀技术粘结牙体组织的选择。本研究检测了五种通用型粘结剂粘结人冠部牙本质的短期体外性能。
根据通用型粘结剂的类型(Prime&Bond Elect、Scotchbond Universal、All-Bond Universal、Clearfil Universal Bond和Futurabond U),将200颗无龋的人第三磨牙分为五组。每组粘结剂采用两种粘结模式(酸蚀冲洗和自酸蚀)。粘结标本在去离子水中保存24小时,或在测试前经过10000次循环的热循环老化处理(N = 10)。进行微拉伸粘结测试(μTBS)、非热循环标本树脂-牙本质界面的透射电子显微镜(TEM)观察以及热循环标本混合层内富含示踪剂的富水区的扫描电子显微镜(SEM)观察。
粘结剂类型和测试条件(有无热循环)均对μTBS有显著影响。每种粘结剂在酸蚀冲洗或自酸蚀应用模式下使用时,与牙本质的μTBS无显著差异。这些粘结剂在酸蚀冲洗粘结模式和自酸蚀粘结模式下形成的混合层分别约为5μm厚和≤0.5μm厚。在所有制备的标本的树脂-牙本质界面内均可识别出富含示踪剂的区域。
通用型粘结剂通用性的提高并未伴随着克服与前代粘结剂相关挑战的技术进步。商业化粘结剂中仍缺乏具有生物保护和生物促进作用的治疗性粘结剂。
通用型粘结剂代表了制造商通过将单瓶自酸蚀粘结剂适用于其他应用模式来在产品设计中引入通用性的尝试,同时不损害其粘结效果。