使用分光光度技术评估两种漱口水对口腔异味的减轻效果。
Evaluation of two mouth rinses in reduction of oral malodor using a spectrophotometric technique.
作者信息
Malhotra Sumit, Yeltiwar R K
机构信息
Department of Periodontology and Oral Implantology, ITS Dental College, Muradnagar, Ghaziabad, Uttar Pradesh, India.
出版信息
J Indian Soc Periodontol. 2011 Jul;15(3):250-4. doi: 10.4103/0972-124X.85669.
BACKGROUND
Various mouth rinses have been used in the treatment of halitosis, but most of the evidence for the efficacy of mouth rinses is anecdotal. In the present study, 0.2% chlorhexidine rinse and an essential oil mouth rinse are compared for their efficacy in reducing the breath mercaptan levels.
MATERIALS AND METHODS
Fifteen patients with the chief complaint of oral malodor were randomly divided into 3 groups and were provided with the respective mouth rinses. Pre rinsing measurements were performed on the Day 1 and no other periodontal treatment was instituted. Post rinsing estimation of mercaptan levels was performed after 7 days.
RESULTS
When comparing chlorhexidine with the essential oil mouth rinse, the reduction in VSCs was highly significant in the chlorhexidine group (P<0.01). However, the reduction in the organoleptic scores was not significant among the two groups. Organoleptic scores showed very highly significant correlations with the VSC concentrations measured by the spectrophotometric method.
CONCLUSION
The spectrophotometric technique employed in this study appears to be a promising new method for evaluation of oral malodor. Chlorhexidine still appears to be the agent of choice as a short term regimen in cases of oral malodor.
背景
各种漱口水已被用于治疗口臭，但大多数关于漱口水疗效的证据都是传闻。在本研究中，比较了0.2%洗必泰漱口水和一种精油漱口水在降低口气硫醇水平方面的疗效。
材料与方法
15名主诉口腔异味的患者被随机分为3组，并给予相应的漱口水。在第1天进行漱口前测量，且未进行其他牙周治疗。7天后进行漱口后硫醇水平的评估。
结果
将洗必泰与精油漱口水进行比较时，洗必泰组挥发性硫化物（VSCs）的降低非常显著（P<0.01）。然而，两组之间感官评分的降低并不显著。感官评分与通过分光光度法测量的VSC浓度显示出非常高度的相关性。
结论
本研究中采用的分光光度技术似乎是一种有前景的评估口腔异味的新方法。在口腔异味病例中，洗必泰作为短期治疗方案似乎仍是首选药物。
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