Elhissi Abdelbary M A, Ahmed Waqar, Hassan Israr Ul, Dhanak Vinod R, D'Emanuele Antony
Institute of Nanotechnology and Bioengineering, School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK.
J Drug Deliv. 2012;2012:837327. doi: 10.1155/2012/837327. Epub 2011 Oct 18.
Carbon nanotubes (CNTs) have been introduced recently as a novel carrier system for both small and large therapeutic molecules. CNTs can be functionalized (i.e., surface engineered) with certain functional groups in order to manipulate their physical or biological properties. In addition to the ability of CNTs to act as carriers for a wide range of therapeutic molecules, their large surface area and possibility to manipulate their surfaces and physical dimensions have been exploited for use in the photothermal destruction of cancer cells. This paper paper will discuss the therapeutic applications of CNTs with a major focus on their applications for the treatment of cancer.
碳纳米管（CNTs）最近作为一种用于小分子和大分子治疗药物的新型载体系统被引入。碳纳米管可以用特定官能团进行功能化（即表面工程），以操控其物理或生物学特性。除了能够作为多种治疗药物的载体外，碳纳米管的大表面积以及操控其表面和物理尺寸的可能性已被用于癌细胞的光热破坏。本文将讨论碳纳米管的治疗应用，主要侧重于其在癌症治疗中的应用。
