Samuelson Kristin W
California School of Professional Psychology, Alliant International University, San Francisco, California, USA.
Dialogues Clin Neurosci. 2011;13(3):346-51. doi: 10.31887/DCNS.2011.13.2/ksamuelson.
Declarative memory dysfunction is associated with post-traumatic stress disorder (PTSD). This paper reviews this literature and presents two frameworks to explain the nature of this dysfunction: that memory deficits are a product of neurobiological abnormalities caused by PTSD and/or that pre-existing memory deficits serve as a risk factor for the development of PTSD following trauma exposure. Brain regions implicated in declarative memory deficits include the hippocampus and prefrontal cortex, and imaging and biochemistry studies as they relate to memory dysfunction are described. Prospective and twin studies provide support for a risk factor model.
陈述性记忆功能障碍与创伤后应激障碍（PTSD）相关。本文回顾了这方面的文献，并提出了两个框架来解释这种功能障碍的本质：记忆缺陷是由PTSD引起的神经生物学异常的产物，和/或先前存在的记忆缺陷是创伤暴露后发生PTSD的危险因素。与陈述性记忆缺陷相关的脑区包括海马体和前额叶皮层，并描述了与记忆功能障碍相关的影像学和生物化学研究。前瞻性研究和双胞胎研究为危险因素模型提供了支持。
