创伤后应激障碍与陈述性记忆功能：综述
Post-traumatic stress disorder and declarative memory functioning: a review.
作者信息
Samuelson Kristin W
机构信息
California School of Professional Psychology, Alliant International University, San Francisco, California, USA.
出版信息
Dialogues Clin Neurosci. 2011;13(3):346-51. doi: 10.31887/DCNS.2011.13.2/ksamuelson.
Abstract
Declarative memory dysfunction is associated with post-traumatic stress disorder (PTSD). This paper reviews this literature and presents two frameworks to explain the nature of this dysfunction: that memory deficits are a product of neurobiological abnormalities caused by PTSD and/or that pre-existing memory deficits serve as a risk factor for the development of PTSD following trauma exposure. Brain regions implicated in declarative memory deficits include the hippocampus and prefrontal cortex, and imaging and biochemistry studies as they relate to memory dysfunction are described. Prospective and twin studies provide support for a risk factor model.
摘要
陈述性记忆功能障碍与创伤后应激障碍（PTSD）相关。本文回顾了这方面的文献，并提出了两个框架来解释这种功能障碍的本质：记忆缺陷是由PTSD引起的神经生物学异常的产物，和/或先前存在的记忆缺陷是创伤暴露后发生PTSD的危险因素。与陈述性记忆缺陷相关的脑区包括海马体和前额叶皮层，并描述了与记忆功能障碍相关的影像学和生物化学研究。前瞻性研究和双胞胎研究为危险因素模型提供了支持。
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本文引用的文献
1
Emotion regulation difficulties in trauma survivors: the role of trauma type and PTSD symptom severity.创伤后幸存者的情绪调节困难：创伤类型和 PTSD 症状严重程度的作用。
Behav Ther. 2010 Dec;41(4):587-98. doi: 10.1016/j.beth.2010.04.004. Epub 2010 Jun 30.
2
Reduced hippocampal activity in youth with posttraumatic stress symptoms: an FMRI study.创伤后应激症状青少年的海马活动减少：一项 fMRI 研究。
J Pediatr Psychol. 2010 Jun;35(5):559-69. doi: 10.1093/jpepsy/jsp112. Epub 2009 Dec 7.
3
Smaller amygdala volume and reduced anterior cingulate gray matter density associated with history of post-traumatic stress disorder.杏仁核体积较小，前扣带回灰质密度降低与创伤后应激障碍病史有关。
Psychiatry Res. 2009 Dec 30;174(3):210-6. doi: 10.1016/j.pscychresns.2009.06.001. Epub 2009 Nov 13.
4
Neuropsychological functioning in children with posttraumatic stress disorder.创伤后应激障碍儿童的神经心理学功能。
Child Neuropsychol. 2010;16(2):119-33. doi: 10.1080/09297040903190782. Epub 2009 Sep 21.
5
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J Int Neuropsychol Soc. 2009 Nov;15(6):830-9. doi: 10.1017/S1355617709990476. Epub 2009 Aug 25.
6
Verbal learning and memory impairments in posttraumatic stress disorder: the role of encoding strategies.创伤后应激障碍中的言语学习与记忆损伤：编码策略的作用
Psychiatry Res. 2009 Jan 30;165(1-2):68-77. doi: 10.1016/j.psychres.2008.01.001. Epub 2008 Dec 5.
7
Verbal memory and treatment response in post-traumatic stress disorder.创伤后应激障碍中的言语记忆与治疗反应
Br J Psychiatry. 2008 Sep;193(3):254-5. doi: 10.1192/bjp.bp.107.045922.
8
Consistent impaired verbal memory in PTSD: a meta-analysis.创伤后应激障碍中持续存在的言语记忆受损：一项荟萃分析。
J Affect Disord. 2008 Nov;111(1):74-82. doi: 10.1016/j.jad.2008.02.007. Epub 2008 Apr 2.
9
Hippocampal neurochemistry, neuromorphometry, and verbal memory in nondemented older adults.非痴呆老年人的海马神经化学、神经形态测量与言语记忆
Neurology. 2008 Apr 29;70(18):1594-600. doi: 10.1212/01.wnl.0000306314.77311.be. Epub 2008 Mar 26.
10
Neural correlates of associative learning and memory in veterans with posttraumatic stress disorder.创伤后应激障碍退伍军人联想学习与记忆的神经关联
J Psychiatr Res. 2008 Jul;42(8):659-69. doi: 10.1016/j.jpsychires.2007.06.007. Epub 2007 Aug 14.
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