含依非韦伦的抗反转录病毒药物治疗患者中依托孕烯皮下埋植避孕失败。
Contraceptive failure of etonogestrel implant in patients treated with antiretrovirals including efavirenz.
机构信息
Maternité, Hôpital Necker-Enfants Malades, 75015 Paris Descartes, France.
出版信息
Contraception. 2012 Apr;85(4):425-7. doi: 10.1016/j.contraception.2011.09.005. Epub 2011 Oct 27.
Abstract
Contraception for HIV-positive women is a complex issue. Although the use of condoms is recommended, complementary methods of contraception are often prescribed. Antiretroviral therapy can lead to drug interactions and modify the efficacy of hormonal contraception. Two unintended pregnancies suggest that etonogestrel implants should be used with caution in patients on efavirenz.
摘要
HIV 阳性女性的避孕是一个复杂的问题。虽然建议使用避孕套，但通常会开处补充避孕方法。抗逆转录病毒疗法会导致药物相互作用，并改变激素避孕的效果。两例意外怀孕表明，依非韦伦治疗的患者应谨慎使用依托孕烯植入剂。
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