在资源有限的环境中为感染艾滋病毒的女性植入杰德雷长效避孕针：对药物相互作用导致意外怀孕的担忧。
Implementing the Jadelle implant for women living with HIV in a resource-limited setting: concerns for drug interactions leading to unintended pregnancies.
作者信息
Perry Sarah H, Swamy Padma, Preidis Geoffrey A, Mwanyumba Anne, Motsa Nozipho, Sarero Hailu N
机构信息
aBaylor College of Medicine, Baylor International Pediatric AIDS Initiative, Children's Foundation bDepartment of Pediatrics, Baylor College of Medicine/Texas Children's Hospital cBaylor Bristol-Myers Squibb Children's Clinical Center of Excellence-Swaziland dKingdom of Swaziland Ministry of Health, Sexual and Reproductive Health Unit, Mbabane, Swaziland.
出版信息
AIDS. 2014 Mar 13;28(5):791-3. doi: 10.1097/QAD.0000000000000177.
An analysis of 570 HIV-infected women in Swaziland using the Jadelle implant showed that age, condom use, the provider who placed the implant, and CD4 cell count had no effect on unintentional pregnancy rates. Antiretroviral regimen at the time of pregnancy, however, correlated with pregnancy outcomes (P < 0.001). None of the women on nevirapine or lopinavir/ritonavir-based regimens (n = 208 and 13, respectively) became pregnant, whereas 15 women on efavirenz (n = 121; 12.4%) became pregnant.
一项针对斯威士兰570名感染艾滋病毒女性使用Jadelle植入剂的分析表明，年龄、是否使用避孕套、植入植入剂的医护人员以及CD4细胞计数对意外怀孕率均无影响。然而，怀孕时的抗逆转录病毒治疗方案与妊娠结局相关（P < 0.001）。接受奈韦拉平或洛匹那韦/利托那韦治疗方案的女性（分别为n = 208和13）均未怀孕，而接受依非韦伦治疗的121名女性中有15名（12.4%）怀孕。
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