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基于化学发光共振能量转移的用于生物分子检测的氧化石墨烯平台。

A graphene oxide platform for the assay of biomolecules based on chemiluminescence resonance energy transfer.

机构信息

State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.

出版信息

Chem Commun (Camb). 2012 Jan 4;48(1):106-8. doi: 10.1039/c1cc15443e. Epub 2011 Oct 31.

DOI:10.1039/c1cc15443e
PMID:22037540
Abstract

The bifunctionality of graphene oxide (GO) that can highly adsorb single-stranded DNA (ssDNA) and effectively quench the emission of organic dyes is reasonably utilized in a chemiluminescence resonance energy transfer (CRET) system, achieving sensitive and selective detection of DNA (H1V1) and protein (thrombin), respectively.

摘要

氧化石墨烯(GO)的双重功能可以高度吸附单链 DNA(ssDNA)并有效猝灭有机染料的发射,这在化学发光共振能量转移(CRET)系统中得到了合理利用,分别实现了对 DNA(H1V1)和蛋白质(凝血酶)的灵敏和选择性检测。

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