基于化学发光共振能量转移的用于生物分子检测的氧化石墨烯平台。
A graphene oxide platform for the assay of biomolecules based on chemiluminescence resonance energy transfer.
机构信息
State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.
出版信息
Chem Commun (Camb). 2012 Jan 4;48(1):106-8. doi: 10.1039/c1cc15443e. Epub 2011 Oct 31.
PMID:22037540
Abstract
The bifunctionality of graphene oxide (GO) that can highly adsorb single-stranded DNA (ssDNA) and effectively quench the emission of organic dyes is reasonably utilized in a chemiluminescence resonance energy transfer (CRET) system, achieving sensitive and selective detection of DNA (H1V1) and protein (thrombin), respectively.
摘要
氧化石墨烯（GO）的双重功能可以高度吸附单链 DNA（ssDNA）并有效猝灭有机染料的发射，这在化学发光共振能量转移（CRET）系统中得到了合理利用，分别实现了对 DNA（H1V1）和蛋白质（凝血酶）的灵敏和选择性检测。
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