Emilia Masci, Luca Santoleri, Francesca Belloni, Luca Bottero, Paolo Stefanini, Giuseppe Faillace, Gianbattista Bertani, Carmela Montinaro, Luigi Mancini, Mauro Longoni
Post-Graduated School of General Surgery, University School of Medicine, Milan, Italy.
Transfus Apher Sci. 2011 Dec;45(3):305-11. doi: 10.1016/j.transci.2011.10.013. Epub 2011 Oct 29.
Hemostasis is of critical importance in achieving a positive outcome in any surgical intervention. Different hemostatic methods can be employed and topical hemostatic agents are used in a wide variety of surgical settings. Procoagulation agents have different hemostatic properties and the choice of a specific one is determined by the type of surgical procedure and bleeding. Hemostatic treatments include fibrin sealants, microfibrillar collagen, gelatin hemostatic agents, oxidized regenerated cellulose and cyanoacrylates adhesives. Surgeons should be familiar with topical hemostatics to ensure an appropriate use. Our purpose is to illustrate the currently available agents, their mechanism of action and their effective applications, in order to ensure an optimal use in operating room.
止血对于任何外科手术取得良好结果都至关重要。可以采用不同的止血方法，局部止血剂在各种手术场景中都有应用。促凝血剂具有不同的止血特性，具体选用哪种取决于手术类型和出血情况。止血治疗包括纤维蛋白密封剂、微纤维胶原蛋白、明胶止血剂、氧化再生纤维素和氰基丙烯酸酯粘合剂。外科医生应熟悉局部止血剂以确保正确使用。我们的目的是阐述当前可用的止血剂、其作用机制及其有效应用，以便在手术室实现最佳使用。
