纳米比亚卡万戈地区的耐氯喹恶性疟原虫疟疾
Chloroquine-resistant Plasmodium falciparum malaria in the Kavango region of Namibia.
作者信息
Sharp B L, Freese J A
机构信息
Research Institute for Diseases in a Tropical Environment of the South African Medical Research Council, Durban.
出版信息
S Afr Med J. 1990 Sep 15;78(6):322-3.
PMID:2204121
Abstract
The sensitivity to chloroquine of Plasmodium falciparum from the Kavango region of Namibia was determined by a 24-hour test in vitro. Twenty-six isolates were successfully tested, of which 11 were resistant to a low degree, schizogony being inhibited at 8 pmol/well. The results of the Dill-Glazko test for the presence of 4-aminoquinolines in urine indicate that chloroquine is not widely used in the area.
摘要
通过24小时体外试验测定了纳米比亚卡万戈地区恶性疟原虫对氯喹的敏感性。成功检测了26个分离株，其中11个有低度抗性，在8皮摩尔/孔时裂体生殖受到抑制。尿液中4-氨基喹啉存在情况的迪尔-格拉兹科试验结果表明，该地区氯喹使用并不广泛。
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