Kuz'mina N N, Brue E, Shaĭkov A V, Isaeva L A, Shakhbazian I E, Giannini E, Iakovleva A A, Puodzhiunene E P, Vorontsov I M, Astrauskene D S
Ter Arkh. 1990;62(5):38-41.
The authors describe the results of prospective multicenter Soviet-American placebo-controlled 6-month investigations concerned with assessment of the therapeutic efficacy of auranofin in juvenile rheumatoid arthritis (JRA). 231 patients with JRA were placed under observation. Auranofin was found to be slightly superior to placebo. The drug was tolerated well. It is noted that in the treatment of JRA, of importance are long (6-month) courses of non-steroidal anti-inflammatory drugs.
作者描述了一项前瞻性多中心苏美联合安慰剂对照的为期6个月的研究结果，该研究旨在评估金诺芬治疗青少年类风湿性关节炎（JRA）的疗效。对231例JRA患者进行了观察。发现金诺芬略优于安慰剂。该药物耐受性良好。值得注意的是，在JRA治疗中，重要的是使用非甾体抗炎药进行长期（6个月）疗程的治疗。
