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用于评估轻度认知障碍的筛查工具比较:初步结果

A comparison of screening tools for the assessment of mild cognitive impairment: preliminary findings.

作者信息

Ahmed Samrah, de Jager Celeste, Wilcock Gordon

机构信息

Oxford Project to Investigate Memory and Ageing (OPTIMA), Nuffield Department of Medicine, Anatomy and Genetics, University of Oxford, Oxford, UK.

出版信息

Neurocase. 2012;18(4):336-51. doi: 10.1080/13554794.2011.608365. Epub 2011 Nov 2.

Abstract

We report a pilot investigation into the utility of screening tools in Mild Cognitive Impairment (MCI). The Addenbrooke's Cognitive Examination-Revised (ACE-R), Montreal Cognitive Assessment (MoCA) and the novel Computer-Administered Neuropsychological Screen for Mild Cognitive Impairment (CANS-MCI) were administered to 20 elderly controls and 15 MCI cases. Non-parametric Mann-Whitney U-tests showed significant differences between groups (p < .0001) on the CANS-MCI and MoCA. The ACE-R and MoCA total scores showed high sensitivity (90%) to MCI. Area under the curve was consistently significant in discriminating controls and MCI for memory scores across all screening instruments. A useful profile of quantitative and qualitative information pertaining to cognitive functioning in MCI can be obtained with the MoCA, ACE-R, and CANS-MCI.

摘要

我们报告了一项关于筛查工具在轻度认知障碍(MCI)中的效用的初步调查。对20名老年对照者和15例MCI患者进行了修订版的Addenbrooke认知检查(ACE-R)、蒙特利尔认知评估(MoCA)以及新型的计算机辅助轻度认知障碍神经心理筛查(CANS-MCI)。非参数曼-惠特尼U检验显示,在CANS-MCI和MoCA上,两组之间存在显著差异(p < .0001)。ACE-R和MoCA总分对MCI表现出高敏感性(90%)。在所有筛查工具中,曲线下面积在区分对照者和MCI的记忆分数方面始终具有显著性。使用MoCA、ACE-R和CANS-MCI可以获得与MCI认知功能相关的有用的定量和定性信息概况。

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