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短肢 Roux-en-Y 重建术治疗抗反流手术失败的作用:单中心 5 年经验。

The role of short-limb Roux-en-Y reconstruction for failed antireflux surgery: a single-center 5-year experience.

机构信息

Department of Surgery, Creighton University Medical Center, 601 North 30th Street, Suite 3700, Omaha, NE 68131, USA.

出版信息

Surg Endosc. 2012 May;26(5):1279-86. doi: 10.1007/s00464-011-2026-1. Epub 2011 Nov 2.

Abstract

INTRODUCTION

Revisionary fundoplication is the mainstay of treatment for failed previous fundoplication, but is not always feasible. We report our experience with use of short-limb Roux-en-Y (RNY) reconstruction for failed antireflux procedures.

METHODS

Prospectively collected data were retrospectively analyzed for morbidity, mortality, pre- and postprocedure symptom scores (scale 0-3), body mass index (BMI), and patient satisfaction (scale 1-10).

RESULTS

Seventy-two patients with 1-4 (median 1) previous antireflux procedures underwent RNY reconstruction, either to gastric pouch (n = 64) or to the esophagus (n = 8). There were 37 laparoscopic, 24 open abdominal, and two combined thoracic-abdominal procedures. Nine additional patients underwent conversion from laparoscopy to open surgery. Mean follow-up of 20.7 months (± 12.9 months) was available in 63 (88%) patients. The overall median scores for heartburn, regurgitation, dysphagia, chest pain, and nausea were 0 or 1. There were 72 major and minor complications noted that affected 33 (46%) patients, with no in-hospital or 30-day mortality observed. The most common complications were anastomotic strictures, bowel obstructions, respiratory complications, and dumping. Mean postoperative BMI was 24.6 (± 4.4) kg/m(2) compared with preoperative BMI of 31.4 (± 6.1) kg/m(2). Mean reported satisfaction score was 8.2 (± 2.1), and 89% of the patients would recommend the procedure to a friend. Pre- and postoperative symptoms could be compared in 57 patients, and significant decrease in median symptom scores for heartburn (2-0, P < 0.05), regurgitation (1-0, P < 0.05), and dysphagia (2-0, P < 0.05) was confirmed. There was an increase in reported nausea (0-1, P < 0.05).

CONCLUSIONS

Short-limb RNY reconstruction is an effective remedial procedure for a subset of patients with failed antireflux surgery, but morbidity is significant.

摘要

介绍

翻修胃底折叠术是治疗先前胃底折叠术失败的主要方法,但并非总是可行。我们报告使用短肢 Roux-en-Y(RNY)重建术治疗失败的抗反流手术的经验。

方法

回顾性分析前瞻性收集的数据,评估发病率、死亡率、术前和术后症状评分(0-3 分)、体重指数(BMI)和患者满意度(1-10 分)。

结果

72 例患者有 1-4 次(中位数 1 次)先前的抗反流手术,接受 RNY 重建,要么重建到胃袋(n=64),要么重建到食管(n=8)。其中 37 例为腹腔镜手术,24 例为开腹手术,2 例为胸腹联合手术。另外 9 例患者从腹腔镜手术转为开腹手术。63 例(88%)患者可获得 20.7 个月(±12.9 个月)的中位随访。总体上,烧心、反流、吞咽困难、胸痛和恶心的中位数评分为 0 或 1。有 72 例主要和次要并发症,影响 33 例(46%)患者,无院内或 30 天死亡率。最常见的并发症是吻合口狭窄、肠梗阻、呼吸并发症和倾倒综合征。术后 BMI 平均值为 24.6(±4.4)kg/m2,术前 BMI 平均值为 31.4(±6.1)kg/m2。平均报告的满意度评分为 8.2(±2.1),89%的患者会向朋友推荐该手术。57 例患者可比较术前和术后症状,确认烧心(2-0,P<0.05)、反流(1-0,P<0.05)和吞咽困难(2-0,P<0.05)的中位数症状评分显著下降,报告的恶心增加(0-1,P<0.05)。

结论

短肢 RNY 重建术是治疗失败的抗反流手术的一个亚组患者的有效补救方法,但发病率很高。

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