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胃底折叠术失败后的 Roux-en-Y 重建。

Roux-en-Y reconstruction for failed fundoplication.

机构信息

Department of Surgery, Creighton University Medical Center, 601 North 30th Street, Suite 3700, Omaha, NE 68131, USA.

出版信息

J Gastrointest Surg. 2009 Dec;13(12):2226-32. doi: 10.1007/s11605-009-0994-4. Epub 2009 Sep 2.

Abstract

BACKGROUND

Redo fundoplication has acceptable outcomes in patients with failed previous fundoplications. However, a subset of patients require Roux-en-Y (RNY) reconstruction for symptom relief.

AIM

The aim of this study was to demonstrate safety and efficacy of RNY reconstruction for failed fundoplications.

METHOD

Retrospective review of data on patients who underwent short-limb RNY gastrojejunostomy (GJ) or esophagojejunostomy (EJ) between the years 2005 and 2007 was performed.

RESULTS

Twenty-two patients underwent RNY reconstructions. Fourteen (64%) patients had one, six (27%) patients had two, and 2 (9%) patients had three previous anti-reflux procedures. RNY GJ was performed in 18 patients and EJ in four patients. Gastrectomy was performed in 13 of these patients. Seven patients (32%) had ten major or minor complications within the 30-day postoperative period, without any mortality observed. At a mean follow-up of 23 months, completed in 21 of these patients (95%), the average heartburn score was 0.38 (range, 0-2). The average regurgitation score was 0.23 (range, 0 to2) and the average dysphagia score was 0.7 (range, 0-2). The mean postoperative BMI was 25.4 compared to a preoperative BMI of 31.

CONCLUSION

RNY reconstruction with GJ or EJ for failed anti-reflux procedures is a safe, valid surgical option in difficult situations, where a redo fundoplication is either non-feasible or expected to fail. However, it is associated with higher morbidity.

摘要

背景

对于先前抗反流手术失败的患者,再次行胃底折叠术(fundoplication)具有可接受的效果。然而,有一部分患者需要行 Roux-en-Y(RNY)重建术以缓解症状。

目的

本研究旨在证明 RNY 重建术治疗失败的抗反流手术的安全性和有效性。

方法

回顾性分析了 2005 年至 2007 年间行短襻 RNY 胃空肠吻合术(GJ)或食管空肠吻合术(EJ)的患者数据。

结果

22 例患者接受了 RNY 重建术。14 例(64%)患者进行了一次手术,6 例(27%)患者进行了两次手术,2 例(9%)患者进行了三次先前的抗反流手术。18 例患者行 RNY GJ,4 例患者行 EJ。其中 13 例患者行胃切除术。7 例(32%)患者在术后 30 天内发生 10 例重大或轻微并发症,但无死亡病例。在这些患者中的 21 例(95%)平均随访 23 个月后,平均烧心评分为 0.38(范围,0-2)。平均反流评分为 0.23(范围,0-2),平均吞咽困难评分为 0.7(范围,0-2)。术后平均 BMI 为 25.4,术前 BMI 为 31。

结论

对于先前抗反流手术失败的患者,再次行 RNY 重建术,包括 GJ 或 EJ,是一种安全、有效的手术选择,适用于再次行胃底折叠术不可行或预计会失败的困难情况。然而,它与较高的发病率相关。

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