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[糖尿病患者高脂蛋白血症的治疗]

[Treatment of hyperlipoproteinemia in patients with diabetes mellitus].

作者信息

Dammann H G, Dreyer M, Wernecke J, Lankers H, Müller P, Simon B

机构信息

Diabetes-Schulungsstation des Krankenhauses Bethanien, Hamburg.

出版信息

Fortschr Med. 1990 May 20;108(15):305-8.

PMID:2204598
Abstract

In a large percentage of cases, diabetes mellitus leads to hyperlipidemia. In addition to the diabetes-related secondary hyperlipidemias, all types of primary disturbances of lipid metabolism can also be observed in diabetics. Depending upon the degree of severity and type of metabolic disorder presenting, not only suitable dietetic treatment, but also the various lipid-lowering drugs, fibrates, nicotinic acid, probucol, cholestyramine and the HMG-CoA reductase inhibitors should be introduced into therapy. As in all groups with an elevated coronary risk, strict management of the lipid levels is mandatory in diabetics, too.

摘要

在很大比例的病例中,糖尿病会导致高脂血症。除了与糖尿病相关的继发性高脂血症外,在糖尿病患者中还可观察到所有类型的原发性脂质代谢紊乱。根据所呈现的代谢紊乱的严重程度和类型,不仅应采用适当的饮食治疗,还应将各种降脂药物,如贝特类、烟酸、普罗布考、考来烯胺和HMG-CoA还原酶抑制剂引入治疗。与所有冠心病风险升高的人群一样,糖尿病患者也必须严格控制血脂水平。

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