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粒细胞肉瘤与艾滋病病毒

Granulocytic sarcoma and HIV.

作者信息

Krause John R, Aburiziq Ibrahim

机构信息

Department of Pathology, Section of Hematopathology, Baylor University Medical Center at Dallas.

出版信息

Proc (Bayl Univ Med Cent). 2011 Oct;24(4):306-8. doi: 10.1080/08998280.2011.11928745.

Abstract

Hematopoietic neoplasms are known to occur in the setting of HIV. Excluding Kaposi's sarcoma, the neoplasms are generally high-grade lymphoproliferative disorders. Granulocytic sarcoma, an extramedullary hematopoietic malignancy that may precede or occur during the course of acute myeloid leukemia, has rarely been described in the HIV population. We present the fourth documented case, to our knowledge, of a granulocytic sarcoma occurring in an HIV-positive individual. This has been associated with a very poor prognostic outcome.

摘要

造血系统肿瘤已知会在艾滋病病毒(HIV)感染的情况下发生。除卡波西肉瘤外,这些肿瘤通常是高级别淋巴增殖性疾病。粒细胞肉瘤是一种髓外造血恶性肿瘤,可能在急性髓系白血病之前或病程中出现,在HIV感染者中很少有描述。据我们所知,我们报告了第四例记录在案的HIV阳性个体发生粒细胞肉瘤的病例。这与非常差的预后结果相关。

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