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[胰腺浆液性囊腺瘤与黏液性囊腺瘤/囊腺癌。临床表现、诊断方法及治疗理念]

[Serous cystadenoma and mucinous cystadenoma/cystadenocarcinoma of the pancreas. Clinical manifestation, diagnostic procedure and therapeutic concept].

作者信息

Löser C, Fölsch U R, Creutfeldt W

机构信息

Abteilung für Gastroenterologie und Endokrinologie, Georg-August-Universität, Göttingen.

出版信息

Leber Magen Darm. 1990 Jul;20(4):173-4, 177-9.

PMID:2204772
Abstract

Cystic neoplasms are rare but in the last ten years more frequently detected tumors of the pancreas. The clinical symptoms as abdominal pain, abdominal mass, diarrhoea or weight loss are rather unspecific. There are no typical laboratory findings. Localization, size and cystic character of these tumors are well documented by ultrasound or abdominal computed tomography while typical features in CT as well as US-guided fine needle biopsy may contribute to further differentiation of the tumors. Exocrine and endocrine pancreatic function are frequently weakened which might falsly lead to the diagnosis of chronic pancreatitis. Because of their malignant potential mucinous cystadenoma should be treated by complete surgical resection while serous cystadenoma are exclusively benign and might therefore be treated conservatively in uncomplicated cases or high-risk patients. The prognosis of pancreatic cystadenocarcinoma is obviously better compared to adenocarcinoma of the pancreas.

摘要

囊性肿瘤很少见,但在过去十年中,胰腺肿瘤的检出频率越来越高。腹痛、腹部肿块、腹泻或体重减轻等临床症状相当不具特异性。没有典型的实验室检查结果。这些肿瘤的定位、大小和囊性特征通过超声或腹部计算机断层扫描能很好地记录下来,而CT的典型特征以及超声引导下的细针活检可能有助于肿瘤的进一步鉴别。胰腺的外分泌和内分泌功能常常减弱,这可能会错误地导致慢性胰腺炎的诊断。由于黏液性囊腺瘤具有恶性潜能,应通过完整的手术切除进行治疗,而浆液性囊腺瘤完全是良性的,因此在无并发症的病例或高危患者中可进行保守治疗。胰腺囊腺癌的预后明显优于胰腺癌。

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引用本文的文献

1
Cystadenomas and cystadenocarcinomas of the pancreas: a multiinstitutional retrospective study of 398 cases. French Surgical Association.胰腺囊腺瘤与囊腺癌:一项对398例病例的多机构回顾性研究。法国外科学会
Ann Surg. 1999 Aug;230(2):152-61. doi: 10.1097/00000658-199908000-00004.