Doberstein C, Kirchner R, Gordon L, Silberman A W, Morgenstern L, Shapiro S
Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California.
Mt Sinai J Med. 1990 Mar;57(2):102-5.
Cystic neoplasms of the pancreas can be easily misdiagnosed and mistreated by the surgeon unfamiliar with the pathology, natural history, and operative strategy specific to these uncommon tumors. The authors have treated nine patients over a seven-year period involving four cystadenocarcinomas, two mucinous cystadenomas, two serous cystadenomas, and one solid and papillary epithelial tumor. Our experience illustrates the inaccuracies in both clinical and pathologic diagnosis. Suspected cystic neoplasms are optimally managed by resection. Their slow growth and late metastasis permits curative surgery after a previous drainage or bypass procedure. An aggressive surgical approach is therefore warranted, and multimodal treatment with radiation and chemotherapy may be clinically applicable to large, invasive cystadenocarcinomas.
胰腺囊性肿瘤很容易被不熟悉这些罕见肿瘤的病理学、自然病史和手术策略的外科医生误诊和误治。作者在七年时间里治疗了9例患者，其中包括4例囊腺癌、2例黏液性囊腺瘤、2例浆液性囊腺瘤和1例实性假乳头状上皮瘤。我们的经验说明了临床和病理诊断中的不准确之处。疑似胰腺囊性肿瘤的最佳治疗方法是手术切除。它们生长缓慢且转移较晚，因此在先前进行引流或旁路手术后仍可进行根治性手术。因此，积极的手术方法是必要的，对于大型浸润性囊腺癌，放疗和化疗的多模式治疗在临床上可能适用。
