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应对抗生素耐药性。

Tackling antibiotic resistance.

机构信息

Department of Biology, 1001 E. Third Street, Indiana University, Bloomington, IN 47405, USA.

出版信息

Nat Rev Microbiol. 2011 Nov 2;9(12):894-6. doi: 10.1038/nrmicro2693.

DOI:10.1038/nrmicro2693
PMID:22048738
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4206945/
Abstract

The development and spread of antibiotic resistance in bacteria is a universal threat to both humans and animals that is generally not preventable but can nevertheless be controlled, and it must be tackled in the most effective ways possible. To explore how the problem of antibiotic resistance might best be addressed, a group of 30 scientists from academia and industry gathered at the Banbury Conference Centre in Cold Spring Harbor, New York, USA, from 16 to 18 May 2011. From these discussions there emerged a priority list of steps that need to be taken to resolve this global crisis.

摘要

细菌对抗生素耐药性的发展和传播对人类和动物都是一种普遍的威胁,一般来说是无法预防的,但仍然可以加以控制,必须尽可能以最有效的方式加以处理。为了探讨如何最好地解决抗生素耐药性的问题,来自学术界和工业界的 30 名科学家于 2011 年 5 月 16 日至 18 日聚集在美国纽约州冷泉港的班伯里会议中心。从这些讨论中,出现了需要采取的一系列优先步骤,以解决这一全球性危机。

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本文引用的文献

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Development of an educational resource on microbes, hygiene and prudent antibiotic use for junior and senior school children.为中小学生开发关于微生物、卫生和谨慎使用抗生素的教育资源。
J Antimicrob Chemother. 2011 Jun;66 Suppl 5:v23-31. doi: 10.1093/jac/dkr133.
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Human nutrition, the gut microbiome and the immune system.人体营养、肠道微生物组与免疫系统。
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Marine natural products.海洋天然产物。
Nat Prod Rep. 2011 Feb;28(2):196-268. doi: 10.1039/c005001f. Epub 2010 Dec 13.
4
The 10 x '20 Initiative: pursuing a global commitment to develop 10 new antibacterial drugs by 2020.“10x '20 倡议”:致力于在 2020 年前开发 10 种新型抗菌药物。
Clin Infect Dis. 2010 Apr 15;50(8):1081-3. doi: 10.1086/652237.
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Hospital and societal costs of antimicrobial-resistant infections in a Chicago teaching hospital: implications for antibiotic stewardship.芝加哥一家教学医院中耐抗菌药物感染的医院及社会成本:对抗生素管理的启示
Clin Infect Dis. 2009 Oct 15;49(8):1175-84. doi: 10.1086/605630.
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Drugs for bad bugs: confronting the challenges of antibacterial discovery.对抗耐药菌的药物:应对抗菌药物研发的挑战
Nat Rev Drug Discov. 2007 Jan;6(1):29-40. doi: 10.1038/nrd2201. Epub 2006 Dec 8.
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Development of daptomycin for gram-positive infections.达托霉素用于革兰氏阳性菌感染的研发。
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Emerging viruses, emerging threat.新型病毒,新的威胁。
Science. 1990 Jan 19;247(4940):279-80. doi: 10.1126/science.2153314.