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一只比格犬视网膜中的异位脑组织:病例报告及文献综述

Ectopic brain tissue in the retina of a beagle dog: a case report and literature review.

作者信息

Allavena Rachel E, Phillips Keli, Andrews Marcus H

机构信息

School of Veterinary Science, University of Queensland, Gatton, Queensland, Australia.

出版信息

Vet Ophthalmol. 2012 May;15(3):183-7. doi: 10.1111/j.1463-5224.2011.00933.x. Epub 2011 Aug 8.

Abstract

Isolated ectopic brain tissue within the orbit is an extremely rare finding and has never been reported in dogs or other domestic species. In this case, a focal choristoma of ectopic grey matter-like tissue was present within the retina of a mature female beagle dog, and consisted of neurons and astrocytes as demonstrated respectively by microtubule-associated protein 2 and glial fibrillary acidic protein immunohistochemistry. The lesion was located within the optic fundus adjacent to the optic disk and surrounded by dysplastic retina. The case is presented with a review of literature on this rare entity.

摘要

眼眶内孤立的异位脑组织是一种极其罕见的发现,在犬类或其他家养动物中从未有过报道。在本病例中,一只成年雌性比格犬的视网膜内存在一个局灶性异位灰质样组织迷离瘤,经微管相关蛋白2和胶质纤维酸性蛋白免疫组织化学分别证实,该迷离瘤由神经元和星形胶质细胞组成。病变位于视盘附近的眼底,周围是发育异常的视网膜。本文报告了该病例,并对有关这一罕见实体的文献进行了综述。

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