临床大肠埃希菌分离株中Rns同源物与定植因子抗原的关联
Association of rns homologs with colonization factor antigens in clinical Escherichia coli isolates.
作者信息
Caron J, Maneval D R, Kaper J B, Scott J R
机构信息
Department of Microbiology and Immunology, Emory University Health Sciences Center, Atlanta, Georgia 30322.
出版信息
Infect Immun. 1990 Oct;58(10):3442-4. doi: 10.1128/iai.58.10.3442-3444.1990.
Abstract
rns is a trans-acting positive regulatory factor required for expression of the colonization factor antigen II (CFA/II) antigens CS1 and CS2 (J. Caron, L. M. Coffield, and J. R. Scott, Proc. Natl. Acad. Sci. USA 86:963-967, 1989). All 35 CFA/II-positive strains hybridized with a rns gene probe, as did all 10 CFA/I strains and all 4 CS4 strains. Hybridization with rns was detected in 25% of non-enterotoxigenic Escherichia coli strains and was not detected in enteric pathogens with low G + C content.
摘要
Rns是一种反式作用的正调控因子，是表达定居因子抗原II（CFA/II）抗原CS1和CS2所必需的（J. 卡隆、L. M. 科菲尔德和J. R. 斯科特，《美国国家科学院院刊》86:963 - 967，1989年）。所有35株CFA/II阳性菌株都与rns基因探针杂交，所有10株CFA/I菌株和所有4株CS4菌株也都如此。在25%的非产肠毒素大肠杆菌菌株中检测到与rns的杂交，而在低G + C含量的肠道病原体中未检测到。
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