EcoHealth Alliance, New York, New York, United States of America.
PLoS One. 2011;6(10):e25361. doi: 10.1371/journal.pone.0025361. Epub 2011 Oct 31.
Medetomidine (0.03 mg/kg) and medetomidine/ketamine (0.05/5.0 and 0.025/2.5 mg/kg), administered by intravenous injection, were evaluated for short-term immobilization of wild-caught variable flying foxes (Pteropus hypomelanus). Medetomidine alone produced incomplete chemical restraint and a stressful, prolonged induction. Both ketamine/medetomidine doses produced a smooth induction and complete immobilization. The combined medetomidine/ketamine dose of 0.025/2.5 mg/kg produced a rapid induction (232±224 sec) with minimal struggling and vocalization, a complete and effective immobilization period, and tended to lead to a faster and better quality recovery than medetomidine alone or a higher dose of medetomidine and ketamine (0.05/5.0 mg/kg), thus reducing holding time and permitting an earlier release of the bat back into the wild.
静脉注射给予 0.03mg/kg 的美托咪定和 0.05/5.0 及 0.025/2.5mg/kg 的美托咪定/氯胺酮,用于评估野生捕获的短尾狐蝠(Pteropus hypomelanus)的短期固定。美托咪定单独使用会导致不完全的化学约束和紧张、延长的诱导期。两种氯胺酮/美托咪定剂量都能产生平稳的诱导和完全的固定。联合使用 0.025/2.5mg/kg 的美托咪定/氯胺酮会导致快速诱导(232±224 秒),挣扎和发声最小,具有完全有效的固定期,并倾向于导致比单独使用美托咪定或更高剂量的美托咪定和氯胺酮(0.05/5.0mg/kg)更快更好的恢复,从而减少了握持时间,并允许更早地将蝙蝠放回野外。