Bonartsev A P, Bonartseva G A, Shaĭtan K V, Kirpichnikov M P
Biomed Khim. 2011 Jul-Aug;57(4):374-91.
Biodegradable biopolymers attract much attention in biology and medicine due to its wide application. The present review is designed to be a comprehensive source for research of biodegradable and biocompatible bacterial polymer, poly(3-hydroxybutyrate). This paper focuses on basic properties of biopolymer: biodegradability and biocompatibility, as well as on biopolymer systems: various materials, devices and compositions on the basis of biopolymer. Application of biopolymer systems based on poly(3-hydroxybutyrate) in medicine as surgical implants, in bioengineering as scaffold for cell cultures, and in pharmacy as drug dosage forms and drug systems is observed in the present review.
可生物降解的生物聚合物因其广泛的应用而在生物学和医学领域备受关注。本综述旨在成为研究可生物降解且生物相容的细菌聚合物聚（3-羟基丁酸酯）的全面资料来源。本文重点关注生物聚合物的基本特性：生物降解性和生物相容性，以及生物聚合物体系：基于生物聚合物的各种材料、装置和组合物。本综述还探讨了基于聚（3-羟基丁酸酯）的生物聚合物体系在医学领域作为外科植入物、在生物工程领域作为细胞培养支架以及在药学领域作为药物剂型和药物系统的应用。
