Ward Biotech Ltd., Glasdrummann, Milltown, Monaghan, Ireland.
Int J Mol Sci. 2011;12(10):6566-96. doi: 10.3390/ijms12106566. Epub 2011 Oct 6.
Antimicrobial peptides constitute a diverse class of naturally occurring antimicrobial molecules which have activity against a wide range of pathogenic microorganisms. Antimicrobial peptides are exciting leads in the development of novel biocidal agents at a time when classical antibiotics are under intense pressure from emerging resistance, and the global industry in antibiotic research and development stagnates. This review will examine the potential of antimicrobial peptides, both natural and synthetic, as novel biocidal agents in the battle against multi-drug resistant pathogen infections.
抗菌肽是一类具有广泛抗菌活性的天然存在的抗菌分子，对抗生素耐药性日益严重、抗生素研发全球产业停滞的今天，它们是开发新型杀菌剂的激动人心的先导。本文综述了天然和合成抗菌肽作为新型杀菌剂在对抗多药耐药性病原体感染方面的潜力。
