Institute of Crop Science, Chinese Academy of Agricultural Sciences, South Xueyuan Road, Haidian District No.80, Beijing 100081, China; E-Mails:
Int J Mol Sci. 2011;12(10):7048-58. doi: 10.3390/ijms12107048. Epub 2011 Oct 20.
Phenolic acids have been identified in a variety of legumes including lima bean, broad bean, common bean, pea, jack bean, goa bean, adzuki bean, hyacinth bean, chicking vetch, garbanzo bean, dral, cow bean, rice bean, mung bean and soybean. The present study was carried out with the following aims: (1) to identify and quantify the individual phenolic acid and determine the total phenolic content (TPC); (2) to assess their antioxidant activity, inhibition activities of α-glucosidase, tyrosinase, and formation of advanced glycation endproducts; and (3) to investigate correlations among the phytochemicals and biological activity. Common bean possesses the highest antioxidant activity and advanced glycation endproducts formation inhibition activity. Adzuki bean has the highest α-glucosidase inhibition activity, and mung bean has the highest tyrosinase inhibition activity. There are significant differences in phytochemical content and functional activities among the bean species investigated. Selecting beans can help treat diseases such as dermatological hyperpigmentation illness, type 2 diabetes and associated cardiovascular diseases.
酚酸已在多种豆类中被鉴定出来，包括利马豆、蚕豆、菜豆、豌豆、刺槐豆、戈亚豆、红豆、青豆、鸡豆、兵豆、水稻豆、绿豆和大豆。本研究旨在：（1）鉴定和定量分析酚酸单体，测定总酚含量（TPC）；（2）评估其抗氧化活性、α-葡萄糖苷酶抑制活性、酪氨酸酶抑制活性和晚期糖基化终产物形成抑制活性；（3）研究植物化学物质与生物活性之间的相关性。菜豆具有最高的抗氧化活性和晚期糖基化终产物形成抑制活性。红豆具有最高的α-葡萄糖苷酶抑制活性，绿豆具有最高的酪氨酸酶抑制活性。在所研究的豆类中，植物化学物质含量和功能活性存在显著差异。选择豆类可以帮助治疗皮肤病性色素沉着病、2 型糖尿病和相关心血管疾病等疾病。
