Microbial Ecology Laboratory, Faculty of Marine Resources, Antofagasta University, Antofagasta 1310000, Chile.
Doctorate Applied Science, Mention Coastal Marine Systems, Faculty of Marine Resources, Antofagasta University, Antofagasta 1310000, Chile.
Mar Drugs. 2011;9(10):2155-2163. doi: 10.3390/md9102155. Epub 2011 Oct 24.
It is known that some strains of Vibrio parahaemolyticus are responsible for gastroenteric diseases caused by the ingestion of marine organisms contaminated with these bacterial strains. Organic products that show inhibitory activity on the growth of the pathogenic V. parahaemolyticus were extracted from a Vibrio native in the north of Chile. The inhibitory organic products were isolated by reverse phase chromatography and permeation by Sephadex LH20, and were characterized by spectroscopic and spectrometric techniques. The results showed that the prevailing active product is oleic acid, which was compared with standards by gas chromatography and high-performance liquid chromatography (HPLC). These active products might be useful for controlling the proliferation of pathogenic clones of V. parahaemolyticus.
已知某些副溶血性弧菌菌株可导致因摄入受这些细菌菌株污染的海洋生物而引起的肠胃疾病。从智利北部的一种弧菌中提取出对致病性副溶血性弧菌生长具有抑制活性的有机产物。采用反相色谱法和 Sephadex LH20 渗透法分离抑制有机产物，并通过光谱和光谱技术进行表征。结果表明，主要的活性产物是油酸，并通过气相色谱法和高效液相色谱法（HPLC）与标准品进行了比较。这些活性产物可能有助于控制致病性副溶血性弧菌克隆的增殖。
