Marzette Lionel, Herndon Leon W
Duke University Eye Center, Durham, NC 27710, USA.
Ophthalmic Surg Lasers Imaging. 2011 Nov-Dec;42(6):453-9. doi: 10.3928/15428877-20111017-03.
To compare the success and complication rates of patients with glaucoma who had an Ex-PRESS mini glaucoma shunt device implantation (Optonol, Ltd., Neve Ilan, Israel) to those who had conventional trabeculectomy.
The records of 76 eyes of 69 consecutive subjects who had Ex-PRESS implants and 77 eyes of 65 consecutive controls who had trabeculectomy procedures were reviewed. All surgeries were performed by one of the authors (LWH). Success was defined as an intraocular pressure (IOP) between 5 and 21 mm Hg in patients who did not require further glaucoma surgery in the eye of note.
The difference in the percentage of cases of postoperative hypotony between the standard trabeculectomy group (16%) and the Ex-PRESS group (4%) was statistically significant (P = .023).
The Ex-PRESS device is at least as effective as the standard trabeculectomy in lowering the IOP of patients with glaucoma, with a significantly lower risk of postoperative hypotony. The data further suggest that the Ex-PRESS device results in an overall greater percentage reduction in IOP than with trabeculectomy, although this did not reach statistical significance.
比较植入Ex-PRESS微型青光眼分流装置（以色列内韦伊兰Optonol有限公司）的青光眼患者与接受传统小梁切除术的患者的手术成功率及并发症发生率。
回顾了69例连续接受Ex-PRESS植入术患者的76只眼以及65例连续接受小梁切除术患者的77只眼的病历记录。所有手术均由作者之一（LWH）完成。成功定义为在未对患眼进行进一步青光眼手术的患者中，眼压（IOP）在5至21毫米汞柱之间。
标准小梁切除术组（16%）与Ex-PRESS组（4%）术后低眼压病例百分比差异具有统计学意义（P = 0.023）。
Ex-PRESS装置在降低青光眼患者眼压方面至少与标准小梁切除术同样有效，且术后低眼压风险显著更低。数据进一步表明，Ex-PRESS装置导致眼压总体降低的百分比高于小梁切除术，尽管这未达到统计学意义。
