Rezk Sherif A, Huang Qin
Department of Pathology & Laboratory Medicine, University of California, Irvine (UCI), USA.
Int J Clin Exp Pathol. 2011;4(7):713-7. Epub 2011 Oct 10.
Extranodal NK/T-cell lymphoma, nasal type, is an aggressive EBV-associated lymphoma that mainly involves the nasal cavity but has also been reported to involve other extranodal sites without nasal involvement. In contrast to aggressive NK cell leukemia (a marrow-based aggressive leukemia of NK-cell origin); extensive bone marrow and blood involvement is extremely uncommon by nasal type NK/T lymphoma. We report a patient with extranodal NK/T-cell lymphoma, nasal type that developed extensive bone marrow involvement during the course of her disease with some overlapping features with aggressive NK-cell leukemia.
鼻型结外NK/T细胞淋巴瘤是一种侵袭性的与EB病毒相关的淋巴瘤,主要累及鼻腔,但也有报道称可累及其他结外部位而无鼻腔受累。与侵袭性NK细胞白血病(一种起源于NK细胞的骨髓侵袭性白血病)不同;鼻型NK/T淋巴瘤极少出现广泛的骨髓和血液受累。我们报告了一例鼻型结外NK/T细胞淋巴瘤患者,该患者在疾病过程中出现了广泛的骨髓受累,具有一些与侵袭性NK细胞白血病重叠的特征。