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核苷二磷酸激酶:在跨学科特征下微生物定植中的多功能效应因子。

Nucleoside-diphosphate-kinase: a pleiotropic effector in microbial colonization under interdisciplinary characterization.

机构信息

Department of Periodontology, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.

出版信息

Microbes Infect. 2012 Mar;14(3):228-37. doi: 10.1016/j.micinf.2011.10.002. Epub 2011 Oct 25.

DOI:10.1016/j.micinf.2011.10.002
PMID:22079150
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3277739/
Abstract

Emerging evidence identifies multiple roles for nucleoside-diphosphate-kinase in host-microbe interaction. We provide the first synopsis of utilization of this molecule by various microorganisms during colonization of host tissues. Additionally, we propose novel mechanisms this effector may participate in, which could be crucial for microbial adaptation in chronic host infection.

摘要

新兴证据表明,核苷二磷酸激酶在宿主-微生物相互作用中具有多种作用。我们首次概述了各种微生物在定植宿主组织过程中对该分子的利用。此外,我们还提出了该效应物可能参与的新机制,这对于微生物在慢性宿主感染中的适应性可能至关重要。

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