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茎尖分生组织中的干细胞维持。

Stem cell maintenance in shoot apical meristems.

机构信息

Department of Botany and Plant Sciences, Center for Plant Cell Biology, Institute of Integrative Genome Biology, University of California, Riverside, CA 92521, United States.

出版信息

Curr Opin Plant Biol. 2012 Feb;15(1):10-6. doi: 10.1016/j.pbi.2011.10.008. Epub 2011 Nov 11.

Abstract

Stem cell homeostasis in shoot apical meristems of higher plants is regulated through a dynamic balance between spatial regulation of gene expression, cell growth patterns and patterns of differentiation. Cell-cell communication mediated by both the local factors and long-range signals have been implicated in stem cell homeostasis. Here we have reviewed recent developments on spatio-temporal regulation of cell-cell communication processes with an emphasis on how ubiquitously utilized signals such as plant hormones function with local factors in mediating stem cell homeostasis. We also provide a brief overview of how the activity of ubiquitously utilized epigenetic regulators are modulated locally to orchestrate gene expression.

摘要

高等植物茎尖分生组织中的干细胞稳态是通过基因表达的空间调节、细胞生长模式和分化模式之间的动态平衡来调节的。细胞间通讯是由局部因子和长距离信号介导的,这与干细胞稳态有关。在这里,我们回顾了细胞间通讯过程时空调节的最新进展,重点介绍了植物激素等广泛使用的信号如何与局部因子一起发挥作用,介导干细胞稳态。我们还简要概述了如何局部调节广泛使用的表观遗传调节剂的活性来协调基因表达。

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