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[通过在不连续密度梯度中对主动脉提取物进行超速离心研究血管壁中的脂蛋白变化]

[Study of lipoprotein changes in the vessel wall by ultracentrifugation of aortic extracts in discontinuous density gradients].

作者信息

Popov A V, Kuznetsov A S

出版信息

Vopr Med Khim. 1979 Mar-Apr;25(2):176-80.

PMID:220802
Abstract

As shown by stepwise density gradient ultracentrifugation, atherogenic lipoproteins pentrating into aorta wall, underwent conversions, which were accompanied by alterations in their hydratation density. The data obtained suggest that complex formation of lipoproteins with components of connective tissue matrix is one of important steps responsible for conversion of atherogenic lipoproteins in vessel wall.

摘要

逐步密度梯度超速离心结果显示,渗透进入主动脉壁的致动脉粥样硬化脂蛋白发生了转化,同时其水化密度也发生了改变。所获得的数据表明,脂蛋白与结缔组织基质成分形成复合物是血管壁内致动脉粥样硬化脂蛋白转化的重要步骤之一。

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