Weizman R, Gil-Ad I, Hermesh H, Munitz H, Laron Z
Hasharon Hospital, Petah Tiqva, Israel.
Clin Neuropharmacol. 1990 Aug;13(4):297-302. doi: 10.1097/00002826-199008000-00003.
Basal morning plasma levels of immunoreactive-beta-endorphin (ir-beta-EP), cortisol, and growth hormone (GH) were assessed in 13 obsessive-compulsive disorder (OCD) patients in comparison to 20 healthy controls. All subjects were drug free for at least 1 year. The mean plasma level of ir-beta-EP was significantly lower (36%) in the OCD patients when compared with the control subjects. The decrease in ir-beta-EP was not accompanied by alteration in cortisol and GH plasma levels.
对13名强迫症（OCD）患者和20名健康对照者的基础早晨血浆免疫反应性β-内啡肽（ir-β-EP）、皮质醇和生长激素（GH）水平进行了评估。所有受试者至少1年未服用药物。与对照者相比，OCD患者的ir-β-EP平均血浆水平显著降低（36%）。ir-β-EP的降低并未伴随皮质醇和GH血浆水平的改变。
