Ming Hsieh Department of Electrical Engineering, University of Southern California, Los Angeles, California 90089-2564, USA.
Magn Reson Med. 2012 May;67(5):1316-23. doi: 10.1002/mrm.23116. Epub 2011 Nov 14.
MRI scans are inefficient when the size of the anatomy under investigation is small relative to the subject's full extent. The field of view must be expanded, and acquisition times accordingly prolonged. Shorter scans are feasible with reduced field of view imaging (rFOV) using outer volume suppression (OVS), a magnetization preparation sequence that attenuates signal outside a region of interest (ROI). This work presents a new OVS sequence with a cylindrical ROI, short duration, and improved tolerance for B(1)+ inhomogeneity. The sequence consists of a nonselective adiabatic tipdown pulse, which provides B(1)+-robust signal suppression, and a fast 2D spiral cylindrical tipback pulse. Analysis of the Bloch equations with transverse initial magnetization reveals a conjugate symmetric constraint for tipback pulses with small flip angles. This property is exploited to achieve two-shot performance from the single-shot tipback pulse. The OVS sequence is validated in phantoms and in vivo with multislice spiral imaging at 3 T. The relative signal-to-noise ratio efficiency of the proposed sequence was 98% in a phantom and 75-90% in vivo. The effectiveness is demonstrated with cardiovascular rFOV imaging, which exhibits improved resolution and reduced artifacts compared to conventional, full field of view imaging.
当所研究的解剖结构相对于受检者的全部范围较小时,MRI 扫描效率低下。必须扩大视野,相应地延长采集时间。使用外部体积抑制(OVS)进行短视野成像(rFOV)可以实现更短的扫描,OVS 是一种磁化准备序列,可衰减感兴趣区域(ROI)外的信号。本工作提出了一种新的具有圆柱形 ROI、短持续时间和对 B(1)+不均匀性更好的耐受性的 OVS 序列。该序列由非选择性绝热翻转脉冲组成,该脉冲可提供 B(1)+稳健的信号抑制,以及快速的 2D 螺旋圆柱形翻转脉冲。对带有小翻转角的翻转脉冲的横向初始磁化的布洛赫方程进行分析,揭示了共轭对称约束。该特性被利用来从单次翻转脉冲实现两拍性能。在 3T 下使用多切片螺旋成像在体模和体内对 OVS 序列进行了验证。在体模中,所提出的序列的相对信噪比效率为 98%,在体内为 75-90%。心血管 rFOV 成像证明了该序列的有效性,与传统的全视野成像相比,它具有更高的分辨率和更少的伪影。