Brunner D, Weissbort J, Fischer M, Bearman J E, Loebl K, Schwartz S, Levin S
Am J Clin Nutr. 1979 Jun;32(6):1342-9. doi: 10.1093/ajcn/32.6.1342.
The effect of a gluttony diet in healthy subjects was studied over an observation period of 12 months. Twenty-six agricultural workers, all of them Yemenite Jews, received a high-caloric, high-fat diet, and the changes in serum cholesterol (CH), high-density-lipoprotein-cholesterol, triglycerides, and body weight were assessed. Yemenite Jews as a group are characterized by low serum CH levels and by a low incidence of coronary artery disease. For a period of 7 months the subjects received a diet of 4553 cal/day, more than double their original "Yemenite diet". After this time they resumed their customary low-caloric diet for 3 months, and thereafter for another 2 months they continued with the high-caloric food regimen. The high-caloric, high-fat diet resulted in the expected increase of serum CH. A similar increase of high-density lipoprotein-CH was found. Serum triglyceride levels changed inversely to those of CH. It is suggested that the altered relation of calories derived from carbohydrates to those derived from fats brought about the decrease of triglycerides, and this irrespective of the increased intake of carbohydrates and fats. The rather small gain of body weight over the trial period--despite the doubled caloric intake--is similar to other studies that showed that the ability of normal individuals to gain weight through overeating varies considerably.
在12个月的观察期内，研究了暴饮暴食饮食对健康受试者的影响。26名农业工人，均为也门裔犹太人，接受了高热量、高脂肪饮食，并评估了血清胆固醇（CH）、高密度脂蛋白胆固醇、甘油三酯和体重的变化。也门裔犹太人作为一个群体，其特点是血清CH水平低且冠状动脉疾病发病率低。在7个月的时间里，受试者每天摄入4553卡路里的饮食，比他们原来的“也门饮食”多一倍多。此后，他们恢复了习惯的低热量饮食3个月，之后又继续高热量饮食方案2个月。高热量、高脂肪饮食导致血清CH如预期那样升高。高密度脂蛋白-CH也有类似升高。血清甘油三酯水平与CH水平呈相反变化。有人认为，碳水化合物热量与脂肪热量之间关系的改变导致了甘油三酯的降低，且这与碳水化合物和脂肪摄入量的增加无关。尽管热量摄入翻倍，但在试验期间体重增加相当少，这与其他研究结果相似，即正常个体通过暴饮暴食增加体重的能力差异很大。
