Department of Dermatology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Exp Dermatol. 2011 Dec;20(12):959-68. doi: 10.1111/j.1600-0625.2011.01389.x.
Scalp pruritus is a common complaint that is considered a diagnostically and therapeutically challenging situation. Scalp skin has a unique neural structure that contains densely innervated hair follicles and dermal vasculature. In spite of the recent advances in our understanding of itch pathophysiology, scalp itching has not been studied as yet. In this review, we summarize the current knowledge on the neurobiology of scalp and hair follicles as well as itch mediators and provide a putative mechanism for scalp itch with special emphasis on neuroanatomy and pathophysiology.
头皮瘙痒是一种常见的症状，被认为是一种具有诊断和治疗挑战性的情况。头皮皮肤具有独特的神经结构，其中包含密集神经支配的毛囊和真皮血管。尽管我们对瘙痒病理生理学的理解最近取得了进展，但头皮瘙痒尚未得到研究。在这篇综述中，我们总结了头皮和毛囊的神经生物学以及瘙痒介质的现有知识，并提供了头皮瘙痒的假设机制，特别强调了神经解剖学和病理生理学。
