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黏附性敷贴对角质层电导率的影响。

Effects of adhesive dressings on stratum corneum conductance.

机构信息

Servizio di Chirurgia Plastica, Centro Diagnostico Italiano, Milano, Italy.

出版信息

Skin Res Technol. 2012 May;18(2):241-4. doi: 10.1111/j.1600-0846.2011.00561.x. Epub 2011 Aug 21.

DOI:10.1111/j.1600-0846.2011.00561.x
PMID:22092993
Abstract

BACKGROUND

Stratum corneum is a fundamental layer of epidermis. It acts as a barrier, with antimicrobial features, regulating skin permeability and integrity as well. Adhesive dressings and their removal could alter this layer, affecting cutaneous water balance and lipid composition of stratum corneum. These changes could be monitored by measurement of cutaneous hydration.

METHODS

Ninety-two patients affected by wounds dressed with adhesive tapes or plasters have been studied. Measurement of skin conductance under tape/plaster and in the surrounding healthy skin, immediately after removal of dressing has been performed. Dressing age, wound localization, and characteristics were also considered.

RESULTS

Adhesive dressings alter significantly stratum corneum conductance. Although healthy skin hydration has significant variations throughout the body, cutaneous conductance under adhesive dressing in different areas displays no significative changes. Moreover, the increase in hydration due to adhesive tapes/plasters showed no association with wound dehiscence.

DISCUSSION

Adhesive dressings cause a significative increase in stratum corneum conductance, acting as a barrier to apocrine secretions. Although different hydration levels have been observed in healthy skin throughout the body, no difference exists under adhesive dressing among different regions, suggesting no contraindications in their employment throughout the body.

CONCLUSION

Increase in cutaneous hydration showed no correlations with wound dehiscence, thus confirming safety and practicality of these dressings.

摘要

背景

角质层是表皮的基本层。它作为屏障,具有抗菌特性,调节皮肤通透性和完整性。粘性敷料及其去除可能会改变这一层,影响皮肤水合和角质层的脂质组成。这些变化可以通过测量皮肤水合度来监测。

方法

研究了 92 例用胶带或膏药包扎的伤口患者。在去除敷料后立即测量胶带/膏药下和周围健康皮肤的皮肤电导率。还考虑了敷料的年龄、伤口位置和特征。

结果

粘性敷料显著改变角质层电导率。尽管健康皮肤的水分含量在全身有明显变化,但不同部位粘性敷料下的皮肤电导率没有明显变化。此外,由于胶带/膏药引起的水分增加与伤口裂开无关。

讨论

粘性敷料会导致角质层电导率显著增加,起到阻止顶泌汗液分泌的作用。尽管全身健康皮肤的水分含量存在差异,但粘性敷料下不同区域之间没有差异,这表明在全身使用这些敷料没有禁忌症。

结论

皮肤水合度的增加与伤口裂开无关,从而证实了这些敷料的安全性和实用性。

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Effects of adhesive dressings on stratum corneum conductance.黏附性敷贴对角质层电导率的影响。
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