Bruno G, Merletti F, Pisu E, Pastore G, Marengo C, Pagano G
Institute of Internal Medicine, University of Turin, Italy.
Diabetes Care. 1990 Oct;13(10):1051-6. doi: 10.2337/diacare.13.10.1051.
The goal of this study was to measure the incidence of insulin-dependent diabetes mellitus (IDDM) during 1984-1986 in residents of Turin, Italy, aged less than 30 yr. The primary data source was the list of all subjects diagnosed with IDDM who attended diabetes clinics in Turin. Other data sources were the general register of death certificates, the list of hospital discharges, and the computerized data base of insulin prescriptions. Eighty incident cases of IDDM were identified during the study in 1,130,284 person-yr for those less than 30 yr of age. Age-adjusted (world standard) incidence rates were 8.05, 8.10, and 6.96/100,000 in the age-groups 0-14, 0-19, and 0-29 yr, respectively. Estimated completeness of the primary data source compared with all other data sources was 91%, whereas the estimated completeness of ascertainment of the registry was 99%. Incidence rates of IDDM in northern Italy compare with those of European countries with low-medium incidence. A population-based register is being established for the province of Turin (951,445 inhabitants aged 0-29 yr) for the collection of incident cases since 1984.
本研究的目的是测定1984 - 1986年期间意大利都灵市年龄小于30岁居民中胰岛素依赖型糖尿病(IDDM)的发病率。主要数据来源是在都灵糖尿病诊所就诊并被诊断为IDDM的所有患者名单。其他数据来源包括死亡证明总登记册、医院出院名单以及胰岛素处方计算机数据库。在该研究期间,在年龄小于30岁的1,130,284人年中确定了80例IDDM新发病例。年龄调整后(世界标准)的发病率在0 - 14岁、0 - 19岁和0 - 29岁年龄组中分别为8.05、8.10和6.96/10万。与所有其他数据来源相比,主要数据来源的估计完整性为91%,而登记处确定病例的估计完整性为99%。意大利北部IDDM的发病率与发病率为中低水平的欧洲国家相当。自1984年以来,正在为都灵省(951,445名年龄在0 - 29岁的居民)建立一个基于人群的登记册,用于收集新发病例。