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1985年至1989年西澳大利亚州0至14岁儿童中胰岛素依赖型糖尿病(IDDM)的发病率。

Incidence of IDDM in Western Australia in children aged 0-14 yr from 1985 to 1989.

作者信息

Kelly H A, Byrne G C

机构信息

Department of Endocrinology and Diabetes, Princess Margaret Hospital for Children, Perth, Western Australia.

出版信息

Diabetes Care. 1992 Apr;15(4):515-7. doi: 10.2337/diacare.15.4.515.

Abstract

OBJECTIVE

To document the incidence of insulin-dependent diabetes mellitus (IDDM) in Western Australia in children aged 0-14 yr between 1985 and 1989 and to test for differences in incidence by year of diagnosis, age of diagnosis, and sex.

RESEARCH DESIGN AND METHODS

A population-based register that used a primary source of case ascertainment (diabetes clinics at teaching hospitals and direct approach to general practitioners and general physicians) and a secondary source (Western Australian Hospital Morbidity Data System) established numerator data. Denominator data were obtained from the Australian Bureau of Statistics.

RESULTS

From 1985 to 1989 inclusive, 235 children in the 0- to 14-yr age-group were diagnosed with IDDM in Western Australia. Case ascertainment was estimated at 99% complete. The mean age-adjusted (developed-world population) annual incidence of IDDM was 13.2 per 100,000 person-yr and there was no evidence of an increasing incidence over the 5 yr. However, girls were more likely than boys to be diagnosed with IDDM in this period (P = 0.006).

CONCLUSIONS

The incidence of IDDM in Western Australia is in the middle range of IDDM incidence in countries throughout the world. The unexpected finding of an increased incidence of IDDM in girls compared with boys needs to be confirmed in a future study.

摘要

目的

记录1985年至1989年间西澳大利亚州0至14岁儿童胰岛素依赖型糖尿病(IDDM)的发病率,并检测按诊断年份、诊断年龄和性别划分的发病率差异。

研究设计与方法

一个基于人群的登记系统,其病例确定的主要来源(教学医院的糖尿病诊所、直接联系全科医生和普通内科医生)和次要来源(西澳大利亚医院发病率数据系统)建立了分子数据。分母数据来自澳大利亚统计局。

结果

在1985年至1989年(含)期间,西澳大利亚州0至14岁年龄组中有235名儿童被诊断为IDDM。病例确定估计完成了99%。IDDM的年龄调整后(发达国家人口)年平均发病率为每10万人年13.2例,且在这5年中没有发病率上升的证据。然而,在此期间,女孩比男孩更有可能被诊断为IDDM(P = 0.006)。

结论

西澳大利亚州IDDM的发病率处于世界各国IDDM发病率的中等范围。女孩IDDM发病率高于男孩这一意外发现需要在未来的研究中得到证实。

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