Wong G W, Leung S S, Oppenheimer S J
Department of Pediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, N.T.
Diabetes Care. 1993 Jun;16(6):926-8. doi: 10.2337/diacare.16.6.926.
To provide reliable data on the incidence of IDDM in southern Chinese children in Hong Kong.
A registry was established in 1991 to collect childhood IDDM cases retrospectively and prospectively from four districts in Hong Kong. The study included all newly diagnosed cases of IDDM with onset < 15 yr of age from 1 January 1986 to 31 December 1990. Primary ascertainment was based on review of medical records at a regional hospital serving the four districts. An independent school survey validated registry data.
The completeness of ascertainment was 93.8%. The age-standardized incidence of IDDM was 2.0/100,000/yr with the 95% confidence interval of 1.2-3.0/100,000/yr for children < 15 yr of age during the study period. The incidence rates/100,000/yr for the three age-groups were: < or = 4 yr, 0.8; 5-9 yr, 2.2; 10-14 yr, 2.8. The incidence for males was 1.5/100,000/yr (95% confidence interval 0.7-2.9/100,000/yr) and for females, 2.4/100,000/yr (95% confidence interval 1.3-4.0/100,000/yr).
This study documents a very low incidence rate of childhood IDDM in southern Chinese in Hong Kong.
提供有关香港中国南方儿童胰岛素依赖型糖尿病（IDDM）发病率的可靠数据。
1991年建立了一个登记处，用于回顾性和前瞻性地收集香港四个地区的儿童IDDM病例。该研究纳入了1986年1月1日至1990年12月31日期间所有新诊断的发病年龄<15岁的IDDM病例。主要通过审查为这四个地区服务的一家地区医院的病历进行确诊。一项独立的学校调查验证了登记处的数据。
确诊的完整性为93.8%。在研究期间，15岁以下儿童IDDM的年龄标准化发病率为2.0/100,000/年，95%置信区间为1.2 - 3.0/100,000/年。三个年龄组的发病率/100,000/年分别为：≤4岁，0.8；5 - 9岁，2.2；10 - 14岁，2.8。男性发病率为1.5/100,000/年（95%置信区间0.7 - 2.9/100,000/年），女性发病率为2.4/100,000/年（95%置信区间1.3 - 4.0/100,000/年）。
本研究记录了香港中国南方儿童IDDM的发病率非常低。
