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囊性纤维化患者肺移植后出现的阿氏瓶霉性心房足菌肿

Scedosporium apiospermum atrial mycetomas after lung transplantation for cystic fibrosis.

作者信息

Miraldi F, Anile M, Ruberto F, Tritapepe L, Puglese F, Quattrucci S, Messina T, Vitolo D, Venuta F

机构信息

Department of Cardiac Surgery, University of Rome Sapienza, Rome, Italy.

出版信息

Transpl Infect Dis. 2012 Apr;14(2):188-91. doi: 10.1111/j.1399-3062.2011.00679.x. Epub 2011 Sep 28.

DOI:10.1111/j.1399-3062.2011.00679.x
PMID:22093620
Abstract

A 37-year-old patient with cystic fibrosis underwent double lung transplantation. She developed disseminated Scedosporium apiospermum infection 2 months after surgery. Along with multiple brain abscesses, lung infection, and chorioretinitis, a cardiac echo revealed 2 large intra-atrial mycetomas floating close to the right upper pulmonary vein orifice. The mycetomas were removed through a trans-atrial approach under cardiopulmonary by pass; histology and cultures confirmed the diagnosis. Despite intensive treatment, the patient succumbed from massive brain hemorrhage on the 10th postoperative day.

摘要

一名37岁的囊性纤维化患者接受了双肺移植手术。术后2个月,她发生了播散性阿皮尤斯德氏霉感染。除了多发性脑脓肿、肺部感染和脉络膜视网膜炎外,心脏超声检查发现右心房有2个大的真菌瘤,漂浮在右上肺静脉口附近。在体外循环下通过经心房途径切除了真菌瘤;组织学检查和培养确诊了诊断。尽管进行了强化治疗,患者在术后第10天因大量脑出血死亡。

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