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基层医疗中 2 型糖尿病患者诊断睡眠呼吸暂停的患病率。

Prevalence of diagnosed sleep apnea among patients with type 2 diabetes in primary care.

机构信息

Department of Medicine, Providence Portland Medical Center, Portland; Department of Medicine, Oregon Health and Science University, Portland.

Providence Medical Group, Portland, OR.

出版信息

Chest. 2012 Jun;141(6):1414-1421. doi: 10.1378/chest.11-1945. Epub 2011 Nov 17.

DOI:10.1378/chest.11-1945
PMID:22095313
Abstract

BACKGROUND

Although up to 90% of patients with type 2 diabetes mellitus (T2DM) have obstructive sleep apnea (OSA), the rate at which primary care providers diagnose OSA in patients with diabetes has not been assessed.

METHODS

A retrospective, population-based, multiclinic study was performed to determine the proportion of patients with T2DM managed in primary care clinics who were given a diagnosis of OSA and to identify factors associated with an OSA diagnosis. Electronic health records of adult patients with a diagnosis of T2DM were reviewed for a coexisting diagnosis of OSA, and the diagnostic prevalence of OSA was compared with the expected prevalence.

RESULTS

A total of 16,066 patients with diabetes with one or more primary care office visits in 27 primary care ambulatory practices during an 18-month period from 2009 to 2010 were identified. Analysis revealed that 18% of the study population received an OSA diagnosis, which is less than the 54% to 94% prevalence reported previously. The 23% prevalence of OSA among obese study patients was lower than the expected 87% prevalence. In a logistic model, male sex, BMI, several chronic conditions, and lower low-density lipoprotein levels and hemoglobin A1c identified patients more likely to carry an OSA diagnosis (likelihood ratio, χ(2) = 1,713; P < .0001).

CONCLUSIONS

Primary care providers underdiagnose OSA in patients with T2DM. Obese men with comorbid chronic health conditions are more likely to receive a diagnosis of OSA. Efforts to improve awareness of the association of OSA with T2DM and to implement OSA screening tools should target primary care physicians.

摘要

背景

尽管多达 90%的 2 型糖尿病(T2DM)患者存在阻塞性睡眠呼吸暂停(OSA),但初级保健提供者在糖尿病患者中诊断 OSA 的比率尚未得到评估。

方法

进行了一项回顾性、基于人群的、多诊所研究,以确定在初级保健诊所管理的 T2DM 患者中被诊断为 OSA 的患者比例,并确定与 OSA 诊断相关的因素。对患有 T2DM 的成年患者的电子健康记录进行了审查,以确定是否存在并存的 OSA 诊断,并且比较了 OSA 的诊断患病率与预期患病率。

结果

在 2009 年至 2010 年的 18 个月期间,从 27 个初级保健门诊中确定了 16066 名患有 T2DM 且有一次或多次初级保健就诊的患者。分析表明,研究人群中有 18%的人被诊断为 OSA,这低于先前报告的 54%至 94%的患病率。肥胖研究患者中 OSA 的 23%患病率低于预期的 87%的患病率。在逻辑模型中,男性,BMI,几种慢性疾病以及较低的低密度脂蛋白水平和血红蛋白 A1c 确定了更有可能携带 OSA 诊断的患者(似然比,χ(2) = 1,713; P <.0001)。

结论

初级保健提供者在 T2DM 患者中诊断 OSA 的能力不足。患有合并慢性健康状况的肥胖男性更有可能被诊断为 OSA。应针对初级保健医生努力提高对 OSA 与 T2DM 之间关联的认识并实施 OSA 筛查工具。

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