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肠道转移性黑色素瘤导致的回结肠套叠。病例报告及文献复习。

Ileocolic intussusception due to intestinal metastatic melanoma. Case report and review of the literature.

作者信息

Alvarez Fernando A, Nicolás Matías, Goransky Jeremías, Vaccaro Carlos A, Beskow Axel, Cavadas Demetrio

机构信息

Department of General Surgery, Hospital Italiano de Buenos Aires, Gascón 450, C1181ACH Buenos Aires, Argentina.

出版信息

Int J Surg Case Rep. 2011;2(6):118-21. doi: 10.1016/j.ijscr.2011.03.001. Epub 2011 Apr 12.

Abstract

The small intestine is a frequent site of melanoma metastases and the most common cause of secondary intestinal tumors. Even though, its presentation with intestinal obstruction due to intussusception is very rare. We present a 47-year-old woman with a medical history of facial melanoma operated 17 years ago and recently diagnosed of cervical recurrence who complained of abdominal pain of one week duration accompanied with vomiting and abdominal distension. Computed tomography (CT) scan revealed marked distension of the small intestine with features suggesting intussusception of the distal ileum. At laparoscopic exploration a massive ileocolic intussusception was found with invagination of the last 60 cm of ileum inside the cecum and ascending colon. Surgical reduction revealed a tumor of approximately 2 cm in the distal end of the intussuscepted intestine acting as the lead point. Resection of non-viable ileum along with the tumor and end-to-end anastomosis was performed. Many other lesions of smaller size were found distantly in the proximal small bowel but were not treated. The patient had a full recovery and was discharged three days after surgery. Pathological examination showed metastatic melanoma and a positron emission tomography (PET) scan confirmed disseminated disease with brain metastasis. The patient died three months after surgery. Intestinal occlusion due to metastatic disease is a rare condition but should be taken into account particularly in patients with history of cancer. Surgical intervention with a mini-invasive laparoscopic approach is feasible. Intestinal resection and anastomosis is mandatory for either curative or palliative intentions providing a satisfactory treatment.

摘要

小肠是黑色素瘤转移的常见部位,也是继发性肠道肿瘤的最常见原因。尽管如此,其因肠套叠导致肠梗阻的情况非常罕见。我们报告一名47岁女性,有17年前面部黑色素瘤手术史,近期诊断为颈部复发,主诉持续一周的腹痛,伴有呕吐和腹胀。计算机断层扫描(CT)显示小肠明显扩张,有提示回肠末端肠套叠的特征。腹腔镜探查发现巨大的回结肠套叠,回肠最后60厘米套入盲肠和升结肠。手术复位显示套叠肠管远端有一个约2厘米的肿瘤作为套叠头部。切除坏死的回肠及肿瘤并进行端端吻合。在近端小肠远处还发现许多其他较小的病变,但未予处理。患者完全康复,术后三天出院。病理检查显示为转移性黑色素瘤,正电子发射断层扫描(PET)证实有脑转移的播散性疾病。患者术后三个月死亡。转移性疾病导致的肠梗阻是一种罕见情况,但特别是有癌症病史的患者应予以考虑。采用微创腹腔镜方法进行手术干预是可行的。出于根治或姑息目的进行肠切除和吻合术可提供令人满意的治疗。

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