Stagnitti F, Orsini S, Martellucci A, Tudisco A, Avallone M, Aiuti F, Di Girolamo V, Stefanelli F, De Angelis Francesco, Di Grazia C, Napoleoni A, Nicodemi S, Cipriani B, Ceci F, Mosillo R, Corelli S, Casciaro G, Spaziani E
G Chir. 2014 Sep-Oct;35(9-10):246-9.
Malignant melanoma is characterized by metastases also to the gastrointestinal tract, especially in the small bowel. The diagnosis is often delayed because unspecific clinical presentation (frequently as chronic iron deficiency anemia, rectal bleeding or intestinal obstruction). We present a case of melanoma of unknown primary site, with clinical presentation of intestinal obstruction. A segmental resection of the ileum was performed including mesentery with lymph nodes. Histology revealed metastatic melanoma from unknown primary. PET and MRI confirmed disseminated disease without brain metastasis.
恶性黑色素瘤的特征还包括转移至胃肠道,尤其是小肠。由于临床表现不具特异性(常表现为慢性缺铁性贫血、直肠出血或肠梗阻),诊断往往会延迟。我们报告一例原发部位不明的黑色素瘤病例,其临床表现为肠梗阻。对回肠进行了包括肠系膜及淋巴结的节段性切除。组织学检查显示为原发部位不明的转移性黑色素瘤。PET和MRI证实存在播散性疾病且无脑转移。