Rancić Natasa, Petrović Branislav, Apostolović Svetlana, Mandić Milan, Antić Ivan
Medicinski fakultet Nis, Institut za javno zdravlje, Nis.
Med Pregl. 2011 Sep-Oct;64(9-10):453-60. doi: 10.2298/mpns1110453r.
Acute myocardial infarction has negative influence on patient's quality of life. The objective of the paper was to assess the health-related quality of life in the patients one month and twelve months after acute myocardial infarction and to compare it with the healthy controls.
A prospective cohort study involved 160 patients aged from 30 to 79 and 240 healthy controls. The health-related quality of life was assessed with the Serbian version of these questionnaires: EuroQuol-5-Dimension and EuroQuolVAS. Angina pectoris was ranked according to the classification of Canadian Cardiovascular Society. Multivariate logistic regression analysis was used.
The healthy controls had significantly higher average scores in EuroQuolVAS compared with the patients one month after acute myocardial infarction (74.35 +/- 9.42 vs 60.50 +/- 12.03, p<0.001), as well as twelve months afte acute myocardial infarction (74.35 +/- 9.42 vs 69.83 +/- 12.06, p<0.001). Significantly lower average ranges in EuroQuol-5-Dimension questionnaire and higher quality of life were found twelve months after acute myocardial infarction than one month after acute myocardial infarction (1.41 +/- 0.26 vs 1.53 +/- 0.26, p<0.001). The average ranges of angina pectoris were significantly lower in all the patients twelve months after acute myocardial infarction compared with the first month (0.78 +/- 0.51 vs 0.91 +/- 0.44, p<0.01). The multivariate regression analysis confirmed thrombolytic therapy, percutaneous transluminal angioplasty and age to be important factors influencing health-related quality of life.
The patients assessed their health condition to be significantly higher twelve months after acute myocardial infarction than one month after it. The health-related quality of life was significantly higher in patients who had undergone the percutaneous intervention than in those who had been treated with the thrombolytic therapy.
急性心肌梗死对患者的生活质量有负面影响。本文的目的是评估急性心肌梗死后1个月和12个月患者的健康相关生活质量，并与健康对照组进行比较。
一项前瞻性队列研究纳入了160例年龄在30至79岁之间的患者和240例健康对照者。使用这些问卷的塞尔维亚语版本评估健康相关生活质量：欧洲五维健康量表（EuroQuol-5-Dimension）和欧洲视觉模拟量表（EuroQuolVAS）。根据加拿大心血管学会的分类对心绞痛进行分级。采用多因素逻辑回归分析。
与急性心肌梗死后1个月的患者相比，健康对照组在欧洲视觉模拟量表上的平均得分显著更高（74.35±9.42对60.50±12.03，p<0.001），与急性心肌梗死后12个月的患者相比也是如此（74.35±9.42对69.83±12.06，p<0.001）。急性心肌梗死后12个月的患者在欧洲五维健康量表问卷中的平均范围显著低于急性心肌梗死后1个月的患者，且生活质量更高（1.41±0.26对1.53±0.26，p<0.001）。与第1个月相比，急性心肌梗死后1年所有患者的心绞痛平均范围显著更低（0.78±0.51对0.91±0.44，p<0.01）。多因素回归分析证实溶栓治疗、经皮腔内血管成形术和年龄是影响健康相关生活质量的重要因素。
患者评估其急性心肌梗死后12个月的健康状况明显高于1个月后。接受经皮介入治疗的患者的健康相关生活质量显著高于接受溶栓治疗的患者。
