Holliman R E, Barker K F, Johnson J D
Public Health Laboratory Service, St George's Hospital, London, UK.
Epidemiol Infect. 1990 Oct;105(2):409-14. doi: 10.1017/s0950268800047981.
Recent publicity concerning congenital toxoplasmosis has generated a demand for serological assessment of pregnant women. Many laboratories are requested to undertake primary screening in these cases. We assessed the latex agglutination test (LAT) findings in 158 specimens with detectable toxoplasma specific IgM derived from pregnant women. The LAT titres ranged from 16 to greater than or equal to 4000 reflecting the variable antibody response observed in acute toxoplasmosis. We recommend that non-reference laboratories test specimens from pregnant women using the LAT at a screening dilution of 1:16 and select all reactive samples for detailed investigation.
近期关于先天性弓形虫病的宣传引发了对孕妇进行血清学评估的需求。许多实验室被要求对这些病例进行初步筛查。我们评估了158份来自孕妇的可检测到弓形虫特异性IgM的标本的乳胶凝集试验（LAT）结果。LAT滴度范围为16至大于或等于4000，反映了急性弓形虫病中观察到的可变抗体反应。我们建议非参考实验室使用LAT以1:16的筛查稀释度检测孕妇标本，并选择所有反应性样本进行详细调查。
